Cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia II and impaired renal function using heparin and the platelet GP IIb/IIIa inhibitor tirofiban as anticoagulant

Andreas Koster, Matthias Loebe, Fritz Mertzlufft, Hermann Kuppe, Roland Hetzer

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

In a patient with heparin-induced thrombocytopenia II and impaired renal function, anticoagulation during cardiopulmonary bypass was successfully performed by the use of unfractionated heparin and the platelet glycoprotein IIb/IIIa inhibitor tirofiban. Postoperative antithrombotic therapy with recombinant hirudin was immediately initiated. This regimen for anticoagulation for cardiopulmonary bypass in patients with heparin-induced thrombocytopenia II appears to be particularly appropriate for patients with impaired renal function or for hospitals without special experience with other alternative anticoagulation strategies.

Original languageEnglish (US)
Pages (from-to)2160-2161
Number of pages2
JournalAnnals of Thoracic Surgery
Volume70
Issue number6
DOIs
StatePublished - Dec 1 2000
Externally publishedYes

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ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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