Cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia II and impaired renal function using heparin and the platelet GP IIb/IIIa inhibitor tirofiban as anticoagulant

Andreas Koster, Matthias Loebe, Fritz Mertzlufft, Hermann Kuppe, Roland Hetzer

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

In a patient with heparin-induced thrombocytopenia II and impaired renal function, anticoagulation during cardiopulmonary bypass was successfully performed by the use of unfractionated heparin and the platelet glycoprotein IIb/IIIa inhibitor tirofiban. Postoperative antithrombotic therapy with recombinant hirudin was immediately initiated. This regimen for anticoagulation for cardiopulmonary bypass in patients with heparin-induced thrombocytopenia II appears to be particularly appropriate for patients with impaired renal function or for hospitals without special experience with other alternative anticoagulation strategies.

Original languageEnglish (US)
Pages (from-to)2160-2161
Number of pages2
JournalAnnals of Thoracic Surgery
Volume70
Issue number6
DOIs
StatePublished - 2000
Externally publishedYes

Fingerprint

tirofiban
Platelet Membrane Glycoprotein IIb
Cardiopulmonary Bypass
Thrombocytopenia
Anticoagulants
Heparin
Blood Platelets
Kidney
Special Hospital
Integrin beta3
Hirudins
Platelet Glycoprotein GPIIb-IIIa Complex

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia II and impaired renal function using heparin and the platelet GP IIb/IIIa inhibitor tirofiban as anticoagulant. / Koster, Andreas; Loebe, Matthias; Mertzlufft, Fritz; Kuppe, Hermann; Hetzer, Roland.

In: Annals of Thoracic Surgery, Vol. 70, No. 6, 2000, p. 2160-2161.

Research output: Contribution to journalArticle

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AU - Kuppe, Hermann

AU - Hetzer, Roland

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