Cardiomyocyte injury to transplant: pediatric management.

Gul H. Dadlani, William G. Harmon, Valeriano C. Simbre, Svjetlana Tisma-Dupanovic, Steven E. Lipshultz

Research output: Contribution to journalReview article

4 Scopus citations

Abstract

Cardiomyocyte injury in pediatric patients has a vast number of causes, which are often distinct from the causes of adult heart failure. However, the management of pediatric heart failure and heart transplantation has generally been inferred from adult studies. New therapies show great promise for the neurohormonal regulation of heart failure and the ability to control immunosuppression after heart transplantation. Large, randomized, multicenter, controlled clinical trials are needed to determine the efficacy of these therapies in this population. This article reviews the current recommendations and evidence-based medicine, where available, for the medical management of myopathic dysfunction and transplantation in pediatric patients.

Original languageEnglish (US)
Pages (from-to)91-97
Number of pages7
JournalCurrent opinion in cardiology
Volume18
Issue number2
DOIs
StatePublished - Mar 2003

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Dadlani, G. H., Harmon, W. G., Simbre, V. C., Tisma-Dupanovic, S., & Lipshultz, S. E. (2003). Cardiomyocyte injury to transplant: pediatric management. Current opinion in cardiology, 18(2), 91-97. https://doi.org/10.1097/00001573-200303000-00003