Cardiomyocyte apoptosis in cocaine-induced myocarditis with involvement of bundle of His and left bundle branch

Gianluca Iacobellis, Walter Kemp

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Cocaine abuse can cause degenerative and inflammatory alterations of the myocardium. Cocaine-induced myocarditis has been previously described, but mostly in chronic cocaine addicts. Among several pathogenetic mechanisms of cocaine-related myocardial damage, the myocardial adrenergic stress and cardiomyocytes apoptosis have been recently proposed. We report an unusual case of myocarditis involving the bundle of His and left bundle branch and cardiac myocytes apoptosis in otherwise healthy occasional cocaine abuser.

Original languageEnglish
Pages (from-to)116-118
Number of pages3
JournalInternational Journal of Cardiology
Volume112
Issue number1
DOIs
StatePublished - Sep 10 2006
Externally publishedYes

Fingerprint

Bundle of His
Myocarditis
Cocaine
Cardiac Myocytes
Apoptosis
Cocaine-Related Disorders
Adrenergic Agents
Myocardium

Keywords

  • Cardiomyocyte apoptosis
  • Cocaine abuse
  • Left bundle branch
  • Myocarditis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Cardiomyocyte apoptosis in cocaine-induced myocarditis with involvement of bundle of His and left bundle branch. / Iacobellis, Gianluca; Kemp, Walter.

In: International Journal of Cardiology, Vol. 112, No. 1, 10.09.2006, p. 116-118.

Research output: Contribution to journalArticle

@article{8986780320ff46c1ab1e8a0ba8f556e0,
title = "Cardiomyocyte apoptosis in cocaine-induced myocarditis with involvement of bundle of His and left bundle branch",
abstract = "Cocaine abuse can cause degenerative and inflammatory alterations of the myocardium. Cocaine-induced myocarditis has been previously described, but mostly in chronic cocaine addicts. Among several pathogenetic mechanisms of cocaine-related myocardial damage, the myocardial adrenergic stress and cardiomyocytes apoptosis have been recently proposed. We report an unusual case of myocarditis involving the bundle of His and left bundle branch and cardiac myocytes apoptosis in otherwise healthy occasional cocaine abuser.",
keywords = "Cardiomyocyte apoptosis, Cocaine abuse, Left bundle branch, Myocarditis",
author = "Gianluca Iacobellis and Walter Kemp",
year = "2006",
month = "9",
day = "10",
doi = "10.1016/j.ijcard.2005.08.052",
language = "English",
volume = "112",
pages = "116--118",
journal = "International Journal of Cardiology",
issn = "0167-5273",
publisher = "Elsevier Ireland Ltd",
number = "1",

}

TY - JOUR

T1 - Cardiomyocyte apoptosis in cocaine-induced myocarditis with involvement of bundle of His and left bundle branch

AU - Iacobellis, Gianluca

AU - Kemp, Walter

PY - 2006/9/10

Y1 - 2006/9/10

N2 - Cocaine abuse can cause degenerative and inflammatory alterations of the myocardium. Cocaine-induced myocarditis has been previously described, but mostly in chronic cocaine addicts. Among several pathogenetic mechanisms of cocaine-related myocardial damage, the myocardial adrenergic stress and cardiomyocytes apoptosis have been recently proposed. We report an unusual case of myocarditis involving the bundle of His and left bundle branch and cardiac myocytes apoptosis in otherwise healthy occasional cocaine abuser.

AB - Cocaine abuse can cause degenerative and inflammatory alterations of the myocardium. Cocaine-induced myocarditis has been previously described, but mostly in chronic cocaine addicts. Among several pathogenetic mechanisms of cocaine-related myocardial damage, the myocardial adrenergic stress and cardiomyocytes apoptosis have been recently proposed. We report an unusual case of myocarditis involving the bundle of His and left bundle branch and cardiac myocytes apoptosis in otherwise healthy occasional cocaine abuser.

KW - Cardiomyocyte apoptosis

KW - Cocaine abuse

KW - Left bundle branch

KW - Myocarditis

UR - http://www.scopus.com/inward/record.url?scp=33747337794&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33747337794&partnerID=8YFLogxK

U2 - 10.1016/j.ijcard.2005.08.052

DO - 10.1016/j.ijcard.2005.08.052

M3 - Article

C2 - 16290291

AN - SCOPUS:33747337794

VL - 112

SP - 116

EP - 118

JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

IS - 1

ER -