Cardiometabolic Disease and Dysfunction Following Spinal Cord Injury: Origins and Guideline-Based Countermeasures

Mark S. Nash; David R. Gater

doi:10.1016/j.pmr.2020.04.005

Cardiometabolic Disease and Dysfunction Following Spinal Cord Injury: Origins and Guideline-Based Countermeasures

Mark S. Nash, David R. Gater

Neurological Surgery

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

The risks and health hazards of the cardiometabolic syndrome (CMS) are commonly reported in persons with spinal cord injuries (SCIs) and disorders. Overweight/obesity, insulin resistance, hypertension, and dyslipidemia are highly prevalent after SCI. Both the CMS diagnosis and physical deconditioning worsen the prognosis for all-cause cardiovascular disease. Evidence suggests a role for physical activity to address these risks, although intense exercise may be required. A lifestyle plan incorporating both exercise and nutrition represents a preferred approach for health management. Improved surveillance for CMS risks and exercise and nutritional management are essential for the preservation of optimal health and independence.

Original language	English (US)
Pages (from-to)	415-436
Number of pages	22
Journal	Physical Medicine and Rehabilitation Clinics of North America
Volume	31
Issue number	3
DOIs	https://doi.org/10.1016/j.pmr.2020.04.005
State	Published - Aug 2020

Keywords

Cardiometabolic disease
Cardiovascular disease
Exercise
Nutrition
Pharmacotherapy
Spinal cord injuries

ASJC Scopus subject areas

Physical Therapy, Sports Therapy and Rehabilitation
Rehabilitation

Access to Document

10.1016/j.pmr.2020.04.005

Cite this

@article{8f4d7ee17fd24adeb90d618166841aa5,

title = "Cardiometabolic Disease and Dysfunction Following Spinal Cord Injury: Origins and Guideline-Based Countermeasures",

abstract = "The risks and health hazards of the cardiometabolic syndrome (CMS) are commonly reported in persons with spinal cord injuries (SCIs) and disorders. Overweight/obesity, insulin resistance, hypertension, and dyslipidemia are highly prevalent after SCI. Both the CMS diagnosis and physical deconditioning worsen the prognosis for all-cause cardiovascular disease. Evidence suggests a role for physical activity to address these risks, although intense exercise may be required. A lifestyle plan incorporating both exercise and nutrition represents a preferred approach for health management. Improved surveillance for CMS risks and exercise and nutritional management are essential for the preservation of optimal health and independence.",

keywords = "Cardiometabolic disease, Cardiovascular disease, Exercise, Nutrition, Pharmacotherapy, Spinal cord injuries",

author = "Nash, {Mark S.} and Gater, {David R.}",

note = "Funding Information: The authors have no conflicts to declare. The work is supported by grants from the Paralyzed Veterans of America (MSN); the U.S. Department of Defense CDMRP (MSN); Field-Initiated, DRRP, and SCIMS grants from the National Institute for Disability, Independent Living, and Rehabilitation Research (MSN and DRG; the Craig H. Nielsen Foundation (MSN), and the Miami Project to Cure Paralysis (MSN). Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = aug,

doi = "10.1016/j.pmr.2020.04.005",

language = "English (US)",

volume = "31",

pages = "415--436",

journal = "Physical Medicine and Rehabilitation Clinics of North America",

issn = "1047-9651",

publisher = "W.B. Saunders Ltd",

number = "3",

}

TY - JOUR

T1 - Cardiometabolic Disease and Dysfunction Following Spinal Cord Injury

T2 - Origins and Guideline-Based Countermeasures

AU - Nash, Mark S.

AU - Gater, David R.

N1 - Funding Information: The authors have no conflicts to declare. The work is supported by grants from the Paralyzed Veterans of America (MSN); the U.S. Department of Defense CDMRP (MSN); Field-Initiated, DRRP, and SCIMS grants from the National Institute for Disability, Independent Living, and Rehabilitation Research (MSN and DRG; the Craig H. Nielsen Foundation (MSN), and the Miami Project to Cure Paralysis (MSN). Publisher Copyright: © 2020 Elsevier Inc.

PY - 2020/8

Y1 - 2020/8

N2 - The risks and health hazards of the cardiometabolic syndrome (CMS) are commonly reported in persons with spinal cord injuries (SCIs) and disorders. Overweight/obesity, insulin resistance, hypertension, and dyslipidemia are highly prevalent after SCI. Both the CMS diagnosis and physical deconditioning worsen the prognosis for all-cause cardiovascular disease. Evidence suggests a role for physical activity to address these risks, although intense exercise may be required. A lifestyle plan incorporating both exercise and nutrition represents a preferred approach for health management. Improved surveillance for CMS risks and exercise and nutritional management are essential for the preservation of optimal health and independence.

AB - The risks and health hazards of the cardiometabolic syndrome (CMS) are commonly reported in persons with spinal cord injuries (SCIs) and disorders. Overweight/obesity, insulin resistance, hypertension, and dyslipidemia are highly prevalent after SCI. Both the CMS diagnosis and physical deconditioning worsen the prognosis for all-cause cardiovascular disease. Evidence suggests a role for physical activity to address these risks, although intense exercise may be required. A lifestyle plan incorporating both exercise and nutrition represents a preferred approach for health management. Improved surveillance for CMS risks and exercise and nutritional management are essential for the preservation of optimal health and independence.

KW - Cardiometabolic disease

KW - Cardiovascular disease

KW - Exercise

KW - Nutrition

KW - Pharmacotherapy

KW - Spinal cord injuries

UR - http://www.scopus.com/inward/record.url?scp=85087313535&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85087313535&partnerID=8YFLogxK

U2 - 10.1016/j.pmr.2020.04.005

DO - 10.1016/j.pmr.2020.04.005

M3 - Review article

C2 - 32624103

AN - SCOPUS:85087313535

VL - 31

SP - 415

EP - 436

JO - Physical Medicine and Rehabilitation Clinics of North America

JF - Physical Medicine and Rehabilitation Clinics of North America

SN - 1047-9651

IS - 3

ER -

Cardiometabolic Disease and Dysfunction Following Spinal Cord Injury: Origins and Guideline-Based Countermeasures

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this