Cardiac myxoma (Endocardioma). An immunocytochemical assessment of histogenesis

Azorides R Morales, Gerald Fine, Albert Castro, Mehrdad Nadji

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Eighteen cardiac myoxomas having a variety of histologic patterns were stained for factor VIII related antigen utilizing the peroxidase-antiperoxidase technique. Regardless of their histologic appearance, intense reactivity for factor VIII related antigen was found in tumor cells, whereas four other intracardiac tumors did not stain. Since factor VIII related antigen is known to be elaborated only by endothelial cells and megakaryocytes, it is concluded that cardiac myxoma cells, which similarly synthesize this antigen, originate from endothelial or endocardial cells.

Original languageEnglish
Pages (from-to)896-899
Number of pages4
JournalHuman Pathology
Volume12
Issue number10
DOIs
StatePublished - Jan 1 1981
Externally publishedYes

Fingerprint

Myxoma
von Willebrand Factor
Megakaryocytes
Peroxidase
Neoplasms
Coloring Agents
Endothelial Cells
Antigens

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Cardiac myxoma (Endocardioma). An immunocytochemical assessment of histogenesis. / Morales, Azorides R; Fine, Gerald; Castro, Albert; Nadji, Mehrdad.

In: Human Pathology, Vol. 12, No. 10, 01.01.1981, p. 896-899.

Research output: Contribution to journalArticle

Morales, Azorides R ; Fine, Gerald ; Castro, Albert ; Nadji, Mehrdad. / Cardiac myxoma (Endocardioma). An immunocytochemical assessment of histogenesis. In: Human Pathology. 1981 ; Vol. 12, No. 10. pp. 896-899.
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