Cardiac myxoma (Endocardioma). An immunocytochemical assessment of histogenesis

Azorides R. Morales, Gerald Fine, Albert Castro, Mehrdad Nadji

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


Eighteen cardiac myoxomas having a variety of histologic patterns were stained for factor VIII related antigen utilizing the peroxidase-antiperoxidase technique. Regardless of their histologic appearance, intense reactivity for factor VIII related antigen was found in tumor cells, whereas four other intracardiac tumors did not stain. Since factor VIII related antigen is known to be elaborated only by endothelial cells and megakaryocytes, it is concluded that cardiac myxoma cells, which similarly synthesize this antigen, originate from endothelial or endocardial cells.

Original languageEnglish (US)
Pages (from-to)896-899
Number of pages4
JournalHuman pathology
Issue number10
StatePublished - Oct 1981

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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