Abstract
Eighteen cardiac myoxomas having a variety of histologic patterns were stained for factor VIII related antigen utilizing the peroxidase-antiperoxidase technique. Regardless of their histologic appearance, intense reactivity for factor VIII related antigen was found in tumor cells, whereas four other intracardiac tumors did not stain. Since factor VIII related antigen is known to be elaborated only by endothelial cells and megakaryocytes, it is concluded that cardiac myxoma cells, which similarly synthesize this antigen, originate from endothelial or endocardial cells.
| Original language | English |
|---|---|
| Pages (from-to) | 896-899 |
| Number of pages | 4 |
| Journal | Human Pathology |
| Volume | 12 |
| Issue number | 10 |
| DOIs | |
| State | Published - Jan 1 1981 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Pathology and Forensic Medicine
Cite this
Cardiac myxoma (Endocardioma). An immunocytochemical assessment of histogenesis. / Morales, Azorides R; Fine, Gerald; Castro, Albert; Nadji, Mehrdad.
In: Human Pathology, Vol. 12, No. 10, 01.01.1981, p. 896-899.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cardiac myxoma (Endocardioma). An immunocytochemical assessment of histogenesis
AU - Morales, Azorides R
AU - Fine, Gerald
AU - Castro, Albert
AU - Nadji, Mehrdad
PY - 1981/1/1
Y1 - 1981/1/1
N2 - Eighteen cardiac myoxomas having a variety of histologic patterns were stained for factor VIII related antigen utilizing the peroxidase-antiperoxidase technique. Regardless of their histologic appearance, intense reactivity for factor VIII related antigen was found in tumor cells, whereas four other intracardiac tumors did not stain. Since factor VIII related antigen is known to be elaborated only by endothelial cells and megakaryocytes, it is concluded that cardiac myxoma cells, which similarly synthesize this antigen, originate from endothelial or endocardial cells.
AB - Eighteen cardiac myoxomas having a variety of histologic patterns were stained for factor VIII related antigen utilizing the peroxidase-antiperoxidase technique. Regardless of their histologic appearance, intense reactivity for factor VIII related antigen was found in tumor cells, whereas four other intracardiac tumors did not stain. Since factor VIII related antigen is known to be elaborated only by endothelial cells and megakaryocytes, it is concluded that cardiac myxoma cells, which similarly synthesize this antigen, originate from endothelial or endocardial cells.
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U2 - 10.1016/S0046-8177(81)80194-3
DO - 10.1016/S0046-8177(81)80194-3
M3 - Article
VL - 12
SP - 896
EP - 899
JO - Human Pathology
JF - Human Pathology
SN - 0046-8177
IS - 10
ER -