Cardiac myxoma (Endocardioma). An immunocytochemical assessment of histogenesis

Azorides R. Morales; Gerald Fine; Albert Castro; Mehrdad Nadji

doi:10.1016/S0046-8177(81)80194-3

Cardiac myxoma (Endocardioma). An immunocytochemical assessment of histogenesis

Azorides R. Morales, Gerald Fine, Albert Castro, Mehrdad Nadji

Pathology

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

Eighteen cardiac myoxomas having a variety of histologic patterns were stained for factor VIII related antigen utilizing the peroxidase-antiperoxidase technique. Regardless of their histologic appearance, intense reactivity for factor VIII related antigen was found in tumor cells, whereas four other intracardiac tumors did not stain. Since factor VIII related antigen is known to be elaborated only by endothelial cells and megakaryocytes, it is concluded that cardiac myxoma cells, which similarly synthesize this antigen, originate from endothelial or endocardial cells.

Original language	English (US)
Pages (from-to)	896-899
Number of pages	4
Journal	Human pathology
Volume	12
Issue number	10
DOIs	https://doi.org/10.1016/S0046-8177(81)80194-3
State	Published - Oct 1981

ASJC Scopus subject areas

Pathology and Forensic Medicine

Access to Document

10.1016/S0046-8177(81)80194-3

Fingerprint Dive into the research topics of 'Cardiac myxoma (Endocardioma). An immunocytochemical assessment of histogenesis'. Together they form a unique fingerprint.

Cite this

@article{3c830b3f62254c67afe0104f77637276,

title = "Cardiac myxoma (Endocardioma). An immunocytochemical assessment of histogenesis",

abstract = "Eighteen cardiac myoxomas having a variety of histologic patterns were stained for factor VIII related antigen utilizing the peroxidase-antiperoxidase technique. Regardless of their histologic appearance, intense reactivity for factor VIII related antigen was found in tumor cells, whereas four other intracardiac tumors did not stain. Since factor VIII related antigen is known to be elaborated only by endothelial cells and megakaryocytes, it is concluded that cardiac myxoma cells, which similarly synthesize this antigen, originate from endothelial or endocardial cells.",

author = "Morales, {Azorides R.} and Gerald Fine and Albert Castro and Mehrdad Nadji",

year = "1981",

month = oct,

doi = "10.1016/S0046-8177(81)80194-3",

language = "English (US)",

volume = "12",

pages = "896--899",

journal = "Human Pathology",

issn = "0046-8177",

publisher = "W.B. Saunders Ltd",

number = "10",

}

TY - JOUR

T1 - Cardiac myxoma (Endocardioma). An immunocytochemical assessment of histogenesis

AU - Morales, Azorides R.

AU - Fine, Gerald

AU - Castro, Albert

AU - Nadji, Mehrdad

PY - 1981/10

Y1 - 1981/10

N2 - Eighteen cardiac myoxomas having a variety of histologic patterns were stained for factor VIII related antigen utilizing the peroxidase-antiperoxidase technique. Regardless of their histologic appearance, intense reactivity for factor VIII related antigen was found in tumor cells, whereas four other intracardiac tumors did not stain. Since factor VIII related antigen is known to be elaborated only by endothelial cells and megakaryocytes, it is concluded that cardiac myxoma cells, which similarly synthesize this antigen, originate from endothelial or endocardial cells.

AB - Eighteen cardiac myoxomas having a variety of histologic patterns were stained for factor VIII related antigen utilizing the peroxidase-antiperoxidase technique. Regardless of their histologic appearance, intense reactivity for factor VIII related antigen was found in tumor cells, whereas four other intracardiac tumors did not stain. Since factor VIII related antigen is known to be elaborated only by endothelial cells and megakaryocytes, it is concluded that cardiac myxoma cells, which similarly synthesize this antigen, originate from endothelial or endocardial cells.

UR - http://www.scopus.com/inward/record.url?scp=0019771188&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019771188&partnerID=8YFLogxK

U2 - 10.1016/S0046-8177(81)80194-3

DO - 10.1016/S0046-8177(81)80194-3

M3 - Article

C2 - 6170565

AN - SCOPUS:0019771188

VL - 12

SP - 896

EP - 899

JO - Human Pathology

JF - Human Pathology

SN - 0046-8177

IS - 10

ER -

Cardiac myxoma (Endocardioma). An immunocytochemical assessment of histogenesis

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this