Carcinoembryonic Antigen in Fetal Eccrine Glands: An Immunohistochemical Study

Neal S. Penneys, Recia Kott‐Blumenkranz, B. E. Buck

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Abstract: Developing fetal eccrine glands were examined for the presence of Carcinoembryonic antigen (CEA) using an unlabeled antibody peroxidase‐anti‐peroxidase technique and rabbit antibody to human CEA. The earliest sign of commitment to the formation of an eccrine gtand was the presence of CEA within a single keratinocyte in fetal epidermis. As the eccrine unit evolved, we found CEA in both acrosyringeal cells and the ductal cells. Although the function of CEA in eccrine gland remains undefined, this substance may play an integral role in the earliest development of the gland as well as in its normal function in the adult.

Original languageEnglish (US)
Pages (from-to)281-282
Number of pages2
JournalPediatric Dermatology
Issue number4
StatePublished - Apr 1984

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology


Dive into the research topics of 'Carcinoembryonic Antigen in Fetal Eccrine Glands: An Immunohistochemical Study'. Together they form a unique fingerprint.

Cite this