TY - JOUR
T1 - Carcinoembryonic Antigen in Fetal Eccrine Glands
T2 - An Immunohistochemical Study
AU - Penneys, Neal S.
AU - Kott‐Blumenkranz, Recia
AU - Buck, B. E.
PY - 1984/4
Y1 - 1984/4
N2 - Abstract: Developing fetal eccrine glands were examined for the presence of Carcinoembryonic antigen (CEA) using an unlabeled antibody peroxidase‐anti‐peroxidase technique and rabbit antibody to human CEA. The earliest sign of commitment to the formation of an eccrine gtand was the presence of CEA within a single keratinocyte in fetal epidermis. As the eccrine unit evolved, we found CEA in both acrosyringeal cells and the ductal cells. Although the function of CEA in eccrine gland remains undefined, this substance may play an integral role in the earliest development of the gland as well as in its normal function in the adult.
AB - Abstract: Developing fetal eccrine glands were examined for the presence of Carcinoembryonic antigen (CEA) using an unlabeled antibody peroxidase‐anti‐peroxidase technique and rabbit antibody to human CEA. The earliest sign of commitment to the formation of an eccrine gtand was the presence of CEA within a single keratinocyte in fetal epidermis. As the eccrine unit evolved, we found CEA in both acrosyringeal cells and the ductal cells. Although the function of CEA in eccrine gland remains undefined, this substance may play an integral role in the earliest development of the gland as well as in its normal function in the adult.
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U2 - 10.1111/j.1525-1470.1984.tb01129.x
DO - 10.1111/j.1525-1470.1984.tb01129.x
M3 - Article
C2 - 6208544
AN - SCOPUS:0021163487
VL - 1
SP - 281
EP - 282
JO - Pediatric Dermatology
JF - Pediatric Dermatology
SN - 0736-8046
IS - 4
ER -