Carbon nanotube applications for tissue engineering

Benjamin S. Harrison, Anthony Atala

Research output: Contribution to journalArticle

766 Citations (Scopus)

Abstract

As the field of tissue engineering advances, new tools for better monitoring and evaluating of engineered tissues along with new biomaterials to direct tissue growth are needed. Carbon nanotubes may be an important tissue engineering material for improved tracking of cells, sensing of microenvironments, delivering of transfection agents, and scaffolding for incorporating with the host's body. Using carbon nanotubes for optical, magnetic resonance and radiotracer contrast agents would provide better means of evaluating tissue formation. In addition, monitoring and altering intra and intercellular processes would be useful for design of better engineered tissues. Carbon nanotubes can also be incorporated into scaffolds providing structural reinforcement as well as imparting novel properties such as electrical conductivity into the scaffolds may aid in directing cell growth. Potential cytotoxic effects associated with carbon nanotubes may be mitigated by chemically functionalizing the surface. Overall, carbon nanotubes may play an integral role as unique biomaterial for creating and monitoring engineered tissue.

Original languageEnglish
Pages (from-to)344-353
Number of pages10
JournalBiomaterials
Volume28
Issue number2
DOIs
StatePublished - Jan 1 2007
Externally publishedYes

Fingerprint

Carbon Nanotubes
Tissue Engineering
Tissue engineering
Carbon nanotubes
Tissue
Biocompatible Materials
Biomaterials
Monitoring
Cellular Microenvironment
Electric Conductivity
Cell growth
Magnetic resonance
Scaffolds (biology)
Growth
Scaffolds
Contrast Media
Transfection
Reinforcement
Magnetic Resonance Spectroscopy

Keywords

  • Biosensor
  • Carbon nanotubes
  • Gene transfer
  • Nanocomposite
  • Scaffold

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

Cite this

Carbon nanotube applications for tissue engineering. / Harrison, Benjamin S.; Atala, Anthony.

In: Biomaterials, Vol. 28, No. 2, 01.01.2007, p. 344-353.

Research output: Contribution to journalArticle

Harrison, Benjamin S. ; Atala, Anthony. / Carbon nanotube applications for tissue engineering. In: Biomaterials. 2007 ; Vol. 28, No. 2. pp. 344-353.
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