Candida glabrata infection in gastric carcinoma patient mimicking cutaneous histoplasmosis

Dijana Gugic, Timothy Cleary, Vladimir Vincek

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Candida glabrata is the second most common Candida species detected among hospitalized patients in USA. In tissue C. glabrata present as yeasts, 3-5 microns in size, which are difficult to visualize on H&E stained slides but can be detected on Grocott methenamine silver (GMS) stained slides. The presence of yeasts only, without any hyphal elements, makes C. glabrata difficult to distinguish from Histoplasma capsulatum yeasts that are of similar size. Mycology culture is the method of choice for definitive identification of C. glabrata. Rapid identification is necessary, as mortality rate due to C. glabrata infection in immunocompromised patients is particularly high. We herein report a patient with inoperable gastric carcinoma, who developed cutaneous and septic form of C. glabrata infection.

Original languageEnglish (US)
Article number15
JournalDermatology online journal
Volume14
Issue number2
StatePublished - Feb 1 2008

ASJC Scopus subject areas

  • Dermatology

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