Cancer survival in European adolescents and young adults

G. Gatta, R. Capocaccia, R. De Angelis, C. Stiller, J. W. Coebergh, W. Oberaigner, H. H. Storm, T. Aareleid, M. Jechova, M. Rousarova, T. Hakulinen, G. Hédelin, G. Launoy, J. Macé-Lesec’h, J. Faivre, G. Chaplain, P. M. Carli, J. Este`ve, H. Ziegler, D. Ho¨ lzelG. Schubert Fritschle, L. Tryggvadottir, F. Berrino, C. Allemani, P. Baili, L. Ciccolallo, A. Micheli, E. Taussig, M. Sant, P. Crosignani, G. Tagliabue, S. Ferretti, E. Conti, M. Vercelli, A. Quaglia, F. Pannelli, S. Vitarelli, M. Federico, M. E. Artioli, V. De Lisi, L. Serventi, R. Zanetti, S. Patriarca, L. Gafa`, R. Tumino, F. Falcini, M. Budroni, E. Paci, E. Crocetti, P. Zambon, S. Guzzinati, E. Carrani, D. Lisi, P. Roazzi, M. Santaquilani, A. Tavilla, F. Valente, A. Verdecchia, M. Dalmas, F. Langmark, A. Andersen, J. Rachtan, M. Bielska-Lasota, Z. Wronkowski, M. Zwierko, Paulo Pinheiro, I. Ples?ko, A. Obsitni´kova´, V. Pompe-Kirn, I. Izarzugaza, C. Martinez-Garcia, I. Garau, C. Navarro, M. D. Chirlaque, E. Ardanaz, C. Moreno, J. Galceran, L. Barlow, T. Möller, G. Jundt, J. M. Lutz, M. Usel, O. Visser, S. Godward, E. M.I. Williams, D. Forman, M. J. Quinn, M. Roche, S. Edwards, J. Verne, H. Møller, J. Bell, J. L. Botha, G. Lawrence, M. P. Coleman, R. Black, D. Brewster, J. A. Steward

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Survival of patients aged 15-24 years, diagnosed with cancer during the period of 1990-1994, is described within Europe. Data on 15 101 patients, extracted from the files of the 56 adult cancer registries included in the EUROCARE-3 database, representing 20 European countries, were analysed and compared. Five-year survival for 'all cancers combined' was 75% in males (ranging from 59% in Estonia to 89% in Iceland), and 78% in females (ranging from 59% in Estonia to 89% in Norway). The Northern European countries (except Denmark) and Austria had the highest survival figures, while survival in the Eastern European countries was lower than the European average. Denmark, UK, and the pool of the central European countries, had intermediate survival figures. Haemopoietic tumours were the most common malignancies: 5-year survival was high for Hodgkin's disease (89%), intermediate for non-Hodgkin's lymphoma (68%) and lower for acute lymphoblastic leukaemia (ALL) (47%) and acute myeloblastic leukaemia (AML) (39%). Five-year survival for gonadal germ cell cancers, the second most common malignancy in young adults, was 90%. Five-year survival for the other cancers under consideration was as follows: 89% for skin melanoma, 66% for all Central Nervous System (CNS) tumours, 57% for bone tumours, 58% for osteosarcoma, 42% for Ewing's sarcoma, 57% for soft-tissue sarcomas, 99% for thyroid carcinoma, 82% for uterine cervical carcinoma, and 83% for ovarian carcinoma. For more 'adult-specific tumours', 5-year survival was good for colon (77%) and lung (60%) cancers, and less favourable, compared with adults, for breast cancer (68%). Adolescents (15-19 years) had significantly worse survival than young adults (20-24 years) for all malignancies combined. Survival for Hodgkin's lymphoma, CNS tumours, melanoma and colon cancer showed marked regional variability. Since many of the tumours occurring in young adults are curable, these results should encourage, without delay, efforts to identify obstacles to improving outcome and reducing geographical inequalities in survival for this group of patients.

Original languageEnglish (US)
Pages (from-to)2600-2610
Number of pages11
JournalEuropean Journal of Cancer
Volume39
Issue number18
DOIs
StatePublished - Dec 1 2003
Externally publishedYes

Fingerprint

Young Adult
Survival
Neoplasms
Estonia
Central Nervous System Neoplasms
Denmark
Hodgkin Disease
Melanoma
Carcinoma
Iceland
Ewing's Sarcoma
Austria
Germ Cell and Embryonal Neoplasms
Osteosarcoma
Norway
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Thyroid Neoplasms
Acute Myeloid Leukemia
Sarcoma
Non-Hodgkin's Lymphoma

Keywords

  • Adolescents
  • Cancer survival
  • Europe
  • Population-based cancer registry
  • Young adults

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Gatta, G., Capocaccia, R., De Angelis, R., Stiller, C., Coebergh, J. W., Oberaigner, W., ... Steward, J. A. (2003). Cancer survival in European adolescents and young adults. European Journal of Cancer, 39(18), 2600-2610. https://doi.org/10.1016/j.ejca.2003.09.004

Cancer survival in European adolescents and young adults. / Gatta, G.; Capocaccia, R.; De Angelis, R.; Stiller, C.; Coebergh, J. W.; Oberaigner, W.; Storm, H. H.; Aareleid, T.; Jechova, M.; Rousarova, M.; Hakulinen, T.; Hédelin, G.; Launoy, G.; Macé-Lesec’h, J.; Faivre, J.; Chaplain, G.; Carli, P. M.; Este`ve, J.; Ziegler, H.; Ho¨ lzel, D.; Schubert Fritschle, G.; Tryggvadottir, L.; Berrino, F.; Allemani, C.; Baili, P.; Ciccolallo, L.; Micheli, A.; Taussig, E.; Sant, M.; Crosignani, P.; Tagliabue, G.; Ferretti, S.; Conti, E.; Vercelli, M.; Quaglia, A.; Pannelli, F.; Vitarelli, S.; Federico, M.; Artioli, M. E.; De Lisi, V.; Serventi, L.; Zanetti, R.; Patriarca, S.; Gafa`, L.; Tumino, R.; Falcini, F.; Budroni, M.; Paci, E.; Crocetti, E.; Zambon, P.; Guzzinati, S.; Carrani, E.; Lisi, D.; Roazzi, P.; Santaquilani, M.; Tavilla, A.; Valente, F.; Verdecchia, A.; Dalmas, M.; Langmark, F.; Andersen, A.; Rachtan, J.; Bielska-Lasota, M.; Wronkowski, Z.; Zwierko, M.; Pinheiro, Paulo; Ples?ko, I.; Obsitni´kova´, A.; Pompe-Kirn, V.; Izarzugaza, I.; Martinez-Garcia, C.; Garau, I.; Navarro, C.; Chirlaque, M. D.; Ardanaz, E.; Moreno, C.; Galceran, J.; Barlow, L.; Möller, T.; Jundt, G.; Lutz, J. M.; Usel, M.; Visser, O.; Godward, S.; Williams, E. M.I.; Forman, D.; Quinn, M. J.; Roche, M.; Edwards, S.; Verne, J.; Møller, H.; Bell, J.; Botha, J. L.; Lawrence, G.; Coleman, M. P.; Black, R.; Brewster, D.; Steward, J. A.

In: European Journal of Cancer, Vol. 39, No. 18, 01.12.2003, p. 2600-2610.

Research output: Contribution to journalArticle

Gatta, G, Capocaccia, R, De Angelis, R, Stiller, C, Coebergh, JW, Oberaigner, W, Storm, HH, Aareleid, T, Jechova, M, Rousarova, M, Hakulinen, T, Hédelin, G, Launoy, G, Macé-Lesec’h, J, Faivre, J, Chaplain, G, Carli, PM, Este`ve, J, Ziegler, H, Ho¨ lzel, D, Schubert Fritschle, G, Tryggvadottir, L, Berrino, F, Allemani, C, Baili, P, Ciccolallo, L, Micheli, A, Taussig, E, Sant, M, Crosignani, P, Tagliabue, G, Ferretti, S, Conti, E, Vercelli, M, Quaglia, A, Pannelli, F, Vitarelli, S, Federico, M, Artioli, ME, De Lisi, V, Serventi, L, Zanetti, R, Patriarca, S, Gafa`, L, Tumino, R, Falcini, F, Budroni, M, Paci, E, Crocetti, E, Zambon, P, Guzzinati, S, Carrani, E, Lisi, D, Roazzi, P, Santaquilani, M, Tavilla, A, Valente, F, Verdecchia, A, Dalmas, M, Langmark, F, Andersen, A, Rachtan, J, Bielska-Lasota, M, Wronkowski, Z, Zwierko, M, Pinheiro, P, Ples?ko, I, Obsitni´kova´, A, Pompe-Kirn, V, Izarzugaza, I, Martinez-Garcia, C, Garau, I, Navarro, C, Chirlaque, MD, Ardanaz, E, Moreno, C, Galceran, J, Barlow, L, Möller, T, Jundt, G, Lutz, JM, Usel, M, Visser, O, Godward, S, Williams, EMI, Forman, D, Quinn, MJ, Roche, M, Edwards, S, Verne, J, Møller, H, Bell, J, Botha, JL, Lawrence, G, Coleman, MP, Black, R, Brewster, D & Steward, JA 2003, 'Cancer survival in European adolescents and young adults', European Journal of Cancer, vol. 39, no. 18, pp. 2600-2610. https://doi.org/10.1016/j.ejca.2003.09.004
Gatta G, Capocaccia R, De Angelis R, Stiller C, Coebergh JW, Oberaigner W et al. Cancer survival in European adolescents and young adults. European Journal of Cancer. 2003 Dec 1;39(18):2600-2610. https://doi.org/10.1016/j.ejca.2003.09.004
Gatta, G. ; Capocaccia, R. ; De Angelis, R. ; Stiller, C. ; Coebergh, J. W. ; Oberaigner, W. ; Storm, H. H. ; Aareleid, T. ; Jechova, M. ; Rousarova, M. ; Hakulinen, T. ; Hédelin, G. ; Launoy, G. ; Macé-Lesec’h, J. ; Faivre, J. ; Chaplain, G. ; Carli, P. M. ; Este`ve, J. ; Ziegler, H. ; Ho¨ lzel, D. ; Schubert Fritschle, G. ; Tryggvadottir, L. ; Berrino, F. ; Allemani, C. ; Baili, P. ; Ciccolallo, L. ; Micheli, A. ; Taussig, E. ; Sant, M. ; Crosignani, P. ; Tagliabue, G. ; Ferretti, S. ; Conti, E. ; Vercelli, M. ; Quaglia, A. ; Pannelli, F. ; Vitarelli, S. ; Federico, M. ; Artioli, M. E. ; De Lisi, V. ; Serventi, L. ; Zanetti, R. ; Patriarca, S. ; Gafa`, L. ; Tumino, R. ; Falcini, F. ; Budroni, M. ; Paci, E. ; Crocetti, E. ; Zambon, P. ; Guzzinati, S. ; Carrani, E. ; Lisi, D. ; Roazzi, P. ; Santaquilani, M. ; Tavilla, A. ; Valente, F. ; Verdecchia, A. ; Dalmas, M. ; Langmark, F. ; Andersen, A. ; Rachtan, J. ; Bielska-Lasota, M. ; Wronkowski, Z. ; Zwierko, M. ; Pinheiro, Paulo ; Ples?ko, I. ; Obsitni´kova´, A. ; Pompe-Kirn, V. ; Izarzugaza, I. ; Martinez-Garcia, C. ; Garau, I. ; Navarro, C. ; Chirlaque, M. D. ; Ardanaz, E. ; Moreno, C. ; Galceran, J. ; Barlow, L. ; Möller, T. ; Jundt, G. ; Lutz, J. M. ; Usel, M. ; Visser, O. ; Godward, S. ; Williams, E. M.I. ; Forman, D. ; Quinn, M. J. ; Roche, M. ; Edwards, S. ; Verne, J. ; Møller, H. ; Bell, J. ; Botha, J. L. ; Lawrence, G. ; Coleman, M. P. ; Black, R. ; Brewster, D. ; Steward, J. A. / Cancer survival in European adolescents and young adults. In: European Journal of Cancer. 2003 ; Vol. 39, No. 18. pp. 2600-2610.
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title = "Cancer survival in European adolescents and young adults",
abstract = "Survival of patients aged 15-24 years, diagnosed with cancer during the period of 1990-1994, is described within Europe. Data on 15 101 patients, extracted from the files of the 56 adult cancer registries included in the EUROCARE-3 database, representing 20 European countries, were analysed and compared. Five-year survival for 'all cancers combined' was 75{\%} in males (ranging from 59{\%} in Estonia to 89{\%} in Iceland), and 78{\%} in females (ranging from 59{\%} in Estonia to 89{\%} in Norway). The Northern European countries (except Denmark) and Austria had the highest survival figures, while survival in the Eastern European countries was lower than the European average. Denmark, UK, and the pool of the central European countries, had intermediate survival figures. Haemopoietic tumours were the most common malignancies: 5-year survival was high for Hodgkin's disease (89{\%}), intermediate for non-Hodgkin's lymphoma (68{\%}) and lower for acute lymphoblastic leukaemia (ALL) (47{\%}) and acute myeloblastic leukaemia (AML) (39{\%}). Five-year survival for gonadal germ cell cancers, the second most common malignancy in young adults, was 90{\%}. Five-year survival for the other cancers under consideration was as follows: 89{\%} for skin melanoma, 66{\%} for all Central Nervous System (CNS) tumours, 57{\%} for bone tumours, 58{\%} for osteosarcoma, 42{\%} for Ewing's sarcoma, 57{\%} for soft-tissue sarcomas, 99{\%} for thyroid carcinoma, 82{\%} for uterine cervical carcinoma, and 83{\%} for ovarian carcinoma. For more 'adult-specific tumours', 5-year survival was good for colon (77{\%}) and lung (60{\%}) cancers, and less favourable, compared with adults, for breast cancer (68{\%}). Adolescents (15-19 years) had significantly worse survival than young adults (20-24 years) for all malignancies combined. Survival for Hodgkin's lymphoma, CNS tumours, melanoma and colon cancer showed marked regional variability. Since many of the tumours occurring in young adults are curable, these results should encourage, without delay, efforts to identify obstacles to improving outcome and reducing geographical inequalities in survival for this group of patients.",
keywords = "Adolescents, Cancer survival, Europe, Population-based cancer registry, Young adults",
author = "G. Gatta and R. Capocaccia and {De Angelis}, R. and C. Stiller and Coebergh, {J. W.} and W. Oberaigner and Storm, {H. H.} and T. Aareleid and M. Jechova and M. Rousarova and T. Hakulinen and G. H{\'e}delin and G. Launoy and J. Mac{\'e}-Lesec’h and J. Faivre and G. Chaplain and Carli, {P. M.} and J. Este`ve and H. Ziegler and {Ho¨ lzel}, D. and {Schubert Fritschle}, G. and L. Tryggvadottir and F. Berrino and C. Allemani and P. Baili and L. Ciccolallo and A. Micheli and E. Taussig and M. Sant and P. Crosignani and G. Tagliabue and S. Ferretti and E. Conti and M. Vercelli and A. Quaglia and F. Pannelli and S. Vitarelli and M. Federico and Artioli, {M. E.} and {De Lisi}, V. and L. Serventi and R. Zanetti and S. Patriarca and L. Gafa` and R. Tumino and F. Falcini and M. Budroni and E. Paci and E. Crocetti and P. Zambon and S. Guzzinati and E. Carrani and D. Lisi and P. Roazzi and M. Santaquilani and A. Tavilla and F. Valente and A. Verdecchia and M. Dalmas and F. Langmark and A. Andersen and J. Rachtan and M. Bielska-Lasota and Z. Wronkowski and M. Zwierko and Paulo Pinheiro and I. Ples?ko and A. Obsitni´kova´ and V. Pompe-Kirn and I. Izarzugaza and C. Martinez-Garcia and I. Garau and C. Navarro and Chirlaque, {M. D.} and E. Ardanaz and C. Moreno and J. Galceran and L. Barlow and T. M{\"o}ller and G. Jundt and Lutz, {J. M.} and M. Usel and O. Visser and S. Godward and Williams, {E. M.I.} and D. Forman and Quinn, {M. J.} and M. Roche and S. Edwards and J. Verne and H. M{\o}ller and J. Bell and Botha, {J. L.} and G. Lawrence and Coleman, {M. P.} and R. Black and D. Brewster and Steward, {J. A.}",
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language = "English (US)",
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TY - JOUR

T1 - Cancer survival in European adolescents and young adults

AU - Gatta, G.

AU - Capocaccia, R.

AU - De Angelis, R.

AU - Stiller, C.

AU - Coebergh, J. W.

AU - Oberaigner, W.

AU - Storm, H. H.

AU - Aareleid, T.

AU - Jechova, M.

AU - Rousarova, M.

AU - Hakulinen, T.

AU - Hédelin, G.

AU - Launoy, G.

AU - Macé-Lesec’h, J.

AU - Faivre, J.

AU - Chaplain, G.

AU - Carli, P. M.

AU - Este`ve, J.

AU - Ziegler, H.

AU - Ho¨ lzel, D.

AU - Schubert Fritschle, G.

AU - Tryggvadottir, L.

AU - Berrino, F.

AU - Allemani, C.

AU - Baili, P.

AU - Ciccolallo, L.

AU - Micheli, A.

AU - Taussig, E.

AU - Sant, M.

AU - Crosignani, P.

AU - Tagliabue, G.

AU - Ferretti, S.

AU - Conti, E.

AU - Vercelli, M.

AU - Quaglia, A.

AU - Pannelli, F.

AU - Vitarelli, S.

AU - Federico, M.

AU - Artioli, M. E.

AU - De Lisi, V.

AU - Serventi, L.

AU - Zanetti, R.

AU - Patriarca, S.

AU - Gafa`, L.

AU - Tumino, R.

AU - Falcini, F.

AU - Budroni, M.

AU - Paci, E.

AU - Crocetti, E.

AU - Zambon, P.

AU - Guzzinati, S.

AU - Carrani, E.

AU - Lisi, D.

AU - Roazzi, P.

AU - Santaquilani, M.

AU - Tavilla, A.

AU - Valente, F.

AU - Verdecchia, A.

AU - Dalmas, M.

AU - Langmark, F.

AU - Andersen, A.

AU - Rachtan, J.

AU - Bielska-Lasota, M.

AU - Wronkowski, Z.

AU - Zwierko, M.

AU - Pinheiro, Paulo

AU - Ples?ko, I.

AU - Obsitni´kova´, A.

AU - Pompe-Kirn, V.

AU - Izarzugaza, I.

AU - Martinez-Garcia, C.

AU - Garau, I.

AU - Navarro, C.

AU - Chirlaque, M. D.

AU - Ardanaz, E.

AU - Moreno, C.

AU - Galceran, J.

AU - Barlow, L.

AU - Möller, T.

AU - Jundt, G.

AU - Lutz, J. M.

AU - Usel, M.

AU - Visser, O.

AU - Godward, S.

AU - Williams, E. M.I.

AU - Forman, D.

AU - Quinn, M. J.

AU - Roche, M.

AU - Edwards, S.

AU - Verne, J.

AU - Møller, H.

AU - Bell, J.

AU - Botha, J. L.

AU - Lawrence, G.

AU - Coleman, M. P.

AU - Black, R.

AU - Brewster, D.

AU - Steward, J. A.

PY - 2003/12/1

Y1 - 2003/12/1

N2 - Survival of patients aged 15-24 years, diagnosed with cancer during the period of 1990-1994, is described within Europe. Data on 15 101 patients, extracted from the files of the 56 adult cancer registries included in the EUROCARE-3 database, representing 20 European countries, were analysed and compared. Five-year survival for 'all cancers combined' was 75% in males (ranging from 59% in Estonia to 89% in Iceland), and 78% in females (ranging from 59% in Estonia to 89% in Norway). The Northern European countries (except Denmark) and Austria had the highest survival figures, while survival in the Eastern European countries was lower than the European average. Denmark, UK, and the pool of the central European countries, had intermediate survival figures. Haemopoietic tumours were the most common malignancies: 5-year survival was high for Hodgkin's disease (89%), intermediate for non-Hodgkin's lymphoma (68%) and lower for acute lymphoblastic leukaemia (ALL) (47%) and acute myeloblastic leukaemia (AML) (39%). Five-year survival for gonadal germ cell cancers, the second most common malignancy in young adults, was 90%. Five-year survival for the other cancers under consideration was as follows: 89% for skin melanoma, 66% for all Central Nervous System (CNS) tumours, 57% for bone tumours, 58% for osteosarcoma, 42% for Ewing's sarcoma, 57% for soft-tissue sarcomas, 99% for thyroid carcinoma, 82% for uterine cervical carcinoma, and 83% for ovarian carcinoma. For more 'adult-specific tumours', 5-year survival was good for colon (77%) and lung (60%) cancers, and less favourable, compared with adults, for breast cancer (68%). Adolescents (15-19 years) had significantly worse survival than young adults (20-24 years) for all malignancies combined. Survival for Hodgkin's lymphoma, CNS tumours, melanoma and colon cancer showed marked regional variability. Since many of the tumours occurring in young adults are curable, these results should encourage, without delay, efforts to identify obstacles to improving outcome and reducing geographical inequalities in survival for this group of patients.

AB - Survival of patients aged 15-24 years, diagnosed with cancer during the period of 1990-1994, is described within Europe. Data on 15 101 patients, extracted from the files of the 56 adult cancer registries included in the EUROCARE-3 database, representing 20 European countries, were analysed and compared. Five-year survival for 'all cancers combined' was 75% in males (ranging from 59% in Estonia to 89% in Iceland), and 78% in females (ranging from 59% in Estonia to 89% in Norway). The Northern European countries (except Denmark) and Austria had the highest survival figures, while survival in the Eastern European countries was lower than the European average. Denmark, UK, and the pool of the central European countries, had intermediate survival figures. Haemopoietic tumours were the most common malignancies: 5-year survival was high for Hodgkin's disease (89%), intermediate for non-Hodgkin's lymphoma (68%) and lower for acute lymphoblastic leukaemia (ALL) (47%) and acute myeloblastic leukaemia (AML) (39%). Five-year survival for gonadal germ cell cancers, the second most common malignancy in young adults, was 90%. Five-year survival for the other cancers under consideration was as follows: 89% for skin melanoma, 66% for all Central Nervous System (CNS) tumours, 57% for bone tumours, 58% for osteosarcoma, 42% for Ewing's sarcoma, 57% for soft-tissue sarcomas, 99% for thyroid carcinoma, 82% for uterine cervical carcinoma, and 83% for ovarian carcinoma. For more 'adult-specific tumours', 5-year survival was good for colon (77%) and lung (60%) cancers, and less favourable, compared with adults, for breast cancer (68%). Adolescents (15-19 years) had significantly worse survival than young adults (20-24 years) for all malignancies combined. Survival for Hodgkin's lymphoma, CNS tumours, melanoma and colon cancer showed marked regional variability. Since many of the tumours occurring in young adults are curable, these results should encourage, without delay, efforts to identify obstacles to improving outcome and reducing geographical inequalities in survival for this group of patients.

KW - Adolescents

KW - Cancer survival

KW - Europe

KW - Population-based cancer registry

KW - Young adults

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DO - 10.1016/j.ejca.2003.09.004

M3 - Article

C2 - 14642922

AN - SCOPUS:0344983471

VL - 39

SP - 2600

EP - 2610

JO - European Journal of Cancer

JF - European Journal of Cancer

SN - 0959-8049

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