Cancellous and cortical microparticulate allograft for dental implantation

An experimental study in non-human primates

Theodore Malinin, H. Thomas Temple, Arun Garg

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: A comparison of freeze-dried cancellous and cortical particulate bone allograft was made using a non-human primate model. Methods and Materials: Micro-particulate bone allograft (90-300 μm size) made from either cortical or cancellous bone was used to pack standard bone defects in the lower extremities of baboons, Papio hamadryas. Bone allografts were aseptically processed and freeze dried. Bone allografts were prepared from animals other than those included in this study. Six weeks after bone grafting, the animals were killed. Extremities with defects were radiographed. The bone preparations were sectioned with a diamond saw, inspected grossly, photographed, then fixed, and subjected to histologic and histomorpho-metric analysis. Results: Cylindrical bone defects were healed in all animals. No differences in the healing patterns and new bone formation were detected between defects filled with cortical and cancellous microparticulate bone preparations. Conclusion: Either cortical or cancellous microparticulate bone preparations can be used with equal effectiveness to promote bone regeneration in confined bone defects.

Original languageEnglish
Pages (from-to)420-427
Number of pages8
JournalImplant Dentistry
Volume18
Issue number5
DOIs
StatePublished - Oct 1 2009

Fingerprint

Dental Implantation
Primates
Allografts
Bone and Bones
Papio hamadryas
Diamond
Bone Regeneration
Bone Transplantation
Papio
Osteogenesis
Lower Extremity
Extremities

Keywords

  • Cancellous bone
  • Cortical bone
  • Dental defects
  • Freeze-dried allografts
  • Microparticulate allo-graft

ASJC Scopus subject areas

  • Oral Surgery

Cite this

Cancellous and cortical microparticulate allograft for dental implantation : An experimental study in non-human primates. / Malinin, Theodore; Thomas Temple, H.; Garg, Arun.

In: Implant Dentistry, Vol. 18, No. 5, 01.10.2009, p. 420-427.

Research output: Contribution to journalArticle

Malinin, Theodore ; Thomas Temple, H. ; Garg, Arun. / Cancellous and cortical microparticulate allograft for dental implantation : An experimental study in non-human primates. In: Implant Dentistry. 2009 ; Vol. 18, No. 5. pp. 420-427.
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