Calcium ion release in mechanically disrupted heart cells

W. Glenn L. Kerrick, Philip M. Best

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

In cardiac muscle fibers which have had their sarcolemma disrupted intracellular stores of calcium ions can be released by the same chemical stimuli which cause their release from the sarcoplasmic reticulum of skinned skeletal muscle fibers. These stimuli are increases in calcium or caffeine concentrations and substitution of chloride for propionate or sodium for potassium in solutions bathing the fibers.

Original languageEnglish (US)
Pages (from-to)435-437
Number of pages3
JournalScience
Volume183
Issue number4123
DOIs
StatePublished - Jan 1 1974
Externally publishedYes

ASJC Scopus subject areas

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