Abstract
Bronchopulmonary dysplasia (BPD) is one of the most common sequelae in premature infants who survive after prolonged mechanical ventilation. Its pathogenesis is multifactorial and includes prematurity, perinatal infections, pulmonary volutrauma, oxygen toxicity, and increased pulmonary blood flow due to patent ductus arteriosus. It is characterized by chronic respiratory failure with abnormalities in lung function that can persist into adulthood. This is due to severe alterations in lung development characterized by decreased alveolar and capillary formation plus emphysema, fibrosis, and airway obstruction in more severe cases. The prevention of BPD is based on the avoidance of all the factors that are implicated in its pathogenesis.
| Original language | English (US) |
|---|---|
| Title of host publication | Encyclopedia of Respiratory Medicine, Four-Volume Set |
| Publisher | Elsevier Inc. |
| Pages | 300-305 |
| Number of pages | 6 |
| ISBN (Print) | 9780123708793 |
| DOIs | |
| State | Published - Jan 1 2006 |
| Externally published | Yes |
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Keywords
- Bronchopulmonary dysplasia
- Mechanical ventilation
- Prematurity
- Respiratory failure
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Bronchopulmonary Dysplasia. / Bancalari, Eduardo.
Encyclopedia of Respiratory Medicine, Four-Volume Set. Elsevier Inc., 2006. p. 300-305.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Bronchopulmonary Dysplasia
AU - Bancalari, Eduardo
PY - 2006/1/1
Y1 - 2006/1/1
N2 - Bronchopulmonary dysplasia (BPD) is one of the most common sequelae in premature infants who survive after prolonged mechanical ventilation. Its pathogenesis is multifactorial and includes prematurity, perinatal infections, pulmonary volutrauma, oxygen toxicity, and increased pulmonary blood flow due to patent ductus arteriosus. It is characterized by chronic respiratory failure with abnormalities in lung function that can persist into adulthood. This is due to severe alterations in lung development characterized by decreased alveolar and capillary formation plus emphysema, fibrosis, and airway obstruction in more severe cases. The prevention of BPD is based on the avoidance of all the factors that are implicated in its pathogenesis.
AB - Bronchopulmonary dysplasia (BPD) is one of the most common sequelae in premature infants who survive after prolonged mechanical ventilation. Its pathogenesis is multifactorial and includes prematurity, perinatal infections, pulmonary volutrauma, oxygen toxicity, and increased pulmonary blood flow due to patent ductus arteriosus. It is characterized by chronic respiratory failure with abnormalities in lung function that can persist into adulthood. This is due to severe alterations in lung development characterized by decreased alveolar and capillary formation plus emphysema, fibrosis, and airway obstruction in more severe cases. The prevention of BPD is based on the avoidance of all the factors that are implicated in its pathogenesis.
KW - Bronchopulmonary dysplasia
KW - Mechanical ventilation
KW - Prematurity
KW - Respiratory failure
UR - http://www.scopus.com/inward/record.url?scp=85069285496&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85069285496&partnerID=8YFLogxK
U2 - 10.1016/B0-12-370879-6/00054-5
DO - 10.1016/B0-12-370879-6/00054-5
M3 - Chapter
SN - 9780123708793
SP - 300
EP - 305
BT - Encyclopedia of Respiratory Medicine, Four-Volume Set
PB - Elsevier Inc.
ER -