Bronchopulmonary Dysplasia

Eduardo Bancalari

doi:10.1016/B0-12-370879-6/00054-5

Bronchopulmonary Dysplasia

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Bronchopulmonary dysplasia (BPD) is one of the most common sequelae in premature infants who survive after prolonged mechanical ventilation. Its pathogenesis is multifactorial and includes prematurity, perinatal infections, pulmonary volutrauma, oxygen toxicity, and increased pulmonary blood flow due to patent ductus arteriosus. It is characterized by chronic respiratory failure with abnormalities in lung function that can persist into adulthood. This is due to severe alterations in lung development characterized by decreased alveolar and capillary formation plus emphysema, fibrosis, and airway obstruction in more severe cases. The prevention of BPD is based on the avoidance of all the factors that are implicated in its pathogenesis.

Original language	English (US)
Title of host publication	Encyclopedia of Respiratory Medicine, Four-Volume Set
Publisher	Elsevier Inc.
Pages	300-305
Number of pages	6
ISBN (Print)	9780123708793
DOIs	https://doi.org/10.1016/B0-12-370879-6/00054-5
State	Published - Jan 1 2006
Externally published	Yes

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Keywords

Bronchopulmonary dysplasia
Mechanical ventilation
Prematurity
Respiratory failure

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

Bancalari, E. (2006). Bronchopulmonary Dysplasia. In Encyclopedia of Respiratory Medicine, Four-Volume Set (pp. 300-305). Elsevier Inc.. https://doi.org/10.1016/B0-12-370879-6/00054-5

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Access to Document

10.1016/B0-12-370879-6/00054-5