Abstract
Spectral domain optical coherence tomography (SD-OCT) with ultrahigh resolution can be used to measure precise structures in the context of ophthalmic imaging. We designed an ultrahigh resolution SD-OCT system based on broadband superluminescent diode (SLD) as the light source. An axial resolution of 2.2 μm in tissue, a scan depth of 1.48 mm, and a high sensitivity of 93 dB were achieved by the spectrometer designed. The ultrahigh-resolution SD-OCT system was employed to image the human cornea and retina with a cross-section image of 2048 × 2048 pixels. Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using broadband SLD in a simple way.
| Original language | English |
|---|---|
| Article number | 126006 |
| Journal | Journal of Biomedical Optics |
| Volume | 16 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1 2011 |
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Keywords
- Ophthalmic imaging
- Optical coherence tomography
ASJC Scopus subject areas
- Biomedical Engineering
- Biomaterials
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
Cite this
Broadband superluminescent diode-based ultrahigh resolution optical coherence tomography for ophthalmic imaging. / Zhu, Dexi; Shen, Meixiao; Jiang, Hong; Li, Ming; Wang, Michael Renxun; Wang, Yuhong; Ge, Lili; Qu, Jia; Wang, Jianhua.
In: Journal of Biomedical Optics, Vol. 16, No. 12, 126006, 01.12.2011.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Broadband superluminescent diode-based ultrahigh resolution optical coherence tomography for ophthalmic imaging
AU - Zhu, Dexi
AU - Shen, Meixiao
AU - Jiang, Hong
AU - Li, Ming
AU - Wang, Michael Renxun
AU - Wang, Yuhong
AU - Ge, Lili
AU - Qu, Jia
AU - Wang, Jianhua
PY - 2011/12/1
Y1 - 2011/12/1
N2 - Spectral domain optical coherence tomography (SD-OCT) with ultrahigh resolution can be used to measure precise structures in the context of ophthalmic imaging. We designed an ultrahigh resolution SD-OCT system based on broadband superluminescent diode (SLD) as the light source. An axial resolution of 2.2 μm in tissue, a scan depth of 1.48 mm, and a high sensitivity of 93 dB were achieved by the spectrometer designed. The ultrahigh-resolution SD-OCT system was employed to image the human cornea and retina with a cross-section image of 2048 × 2048 pixels. Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using broadband SLD in a simple way.
AB - Spectral domain optical coherence tomography (SD-OCT) with ultrahigh resolution can be used to measure precise structures in the context of ophthalmic imaging. We designed an ultrahigh resolution SD-OCT system based on broadband superluminescent diode (SLD) as the light source. An axial resolution of 2.2 μm in tissue, a scan depth of 1.48 mm, and a high sensitivity of 93 dB were achieved by the spectrometer designed. The ultrahigh-resolution SD-OCT system was employed to image the human cornea and retina with a cross-section image of 2048 × 2048 pixels. Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using broadband SLD in a simple way.
KW - Ophthalmic imaging
KW - Optical coherence tomography
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UR - http://www.scopus.com/inward/citedby.url?scp=84860586256&partnerID=8YFLogxK
U2 - 10.1117/1.3660314
DO - 10.1117/1.3660314
M3 - Article
C2 - 22191923
AN - SCOPUS:84860586256
VL - 16
JO - Journal of Biomedical Optics
JF - Journal of Biomedical Optics
SN - 1083-3668
IS - 12
M1 - 126006
ER -