Broadband superluminescent diode-based ultrahigh resolution optical coherence tomography for ophthalmic imaging

Dexi Zhu, Meixiao Shen, Hong Jiang, Ming Li, Michael Renxun Wang, Yuhong Wang, Lili Ge, Jia Qu, Jianhua Wang

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Spectral domain optical coherence tomography (SD-OCT) with ultrahigh resolution can be used to measure precise structures in the context of ophthalmic imaging. We designed an ultrahigh resolution SD-OCT system based on broadband superluminescent diode (SLD) as the light source. An axial resolution of 2.2 μm in tissue, a scan depth of 1.48 mm, and a high sensitivity of 93 dB were achieved by the spectrometer designed. The ultrahigh-resolution SD-OCT system was employed to image the human cornea and retina with a cross-section image of 2048 × 2048 pixels. Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using broadband SLD in a simple way.

Original languageEnglish
Article number126006
JournalJournal of Biomedical Optics
Volume16
Issue number12
DOIs
StatePublished - Dec 1 2011

Fingerprint

Optical tomography
Spectral resolution
Diodes
tomography
diodes
spectral resolution
broadband
Imaging techniques
cornea
retina
Light sources
Spectrometers
light sources
Pixels
pixels
spectrometers
Tissue
sensitivity
cross sections

Keywords

  • Ophthalmic imaging
  • Optical coherence tomography

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics

Cite this

Broadband superluminescent diode-based ultrahigh resolution optical coherence tomography for ophthalmic imaging. / Zhu, Dexi; Shen, Meixiao; Jiang, Hong; Li, Ming; Wang, Michael Renxun; Wang, Yuhong; Ge, Lili; Qu, Jia; Wang, Jianhua.

In: Journal of Biomedical Optics, Vol. 16, No. 12, 126006, 01.12.2011.

Research output: Contribution to journalArticle

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