Abstract
We aim to identify the link between placental histological findings and obstetric reports to determine possible risk factors of spontaneous preterm birth (SPTB). We prospectively ascertained birth records and outcomes from all deliveries in our hospital in 1 year. Records were used to determine and stratify for either full-term or preterm spontaneous or indicated (I)" deliveries. We analyzed for risk factor association using χ2 tests and common odds ratio estimates (SPSS v21.0). Our cohort totaled 6088 deliveries: 236 IPTB, 43 SPTB, and 5809 term births. Largely Hispanic, we determined race, parity, prenatal care access, preeclampsia, gestational diabetes, and BMI to be highly associated with SPTB (p < 0.01). Histologically, placentas of women with SPTB were twice as likely to have chronic villitis. We found that chronic villitis is associated with SPTB. Results of this study can be used in increasing the understanding of SPTB.
| Original language | English |
|---|---|
| Pages (from-to) | 226-233 |
| Number of pages | 8 |
| Journal | Fetal and Pediatric Pathology |
| Volume | 33 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jan 1 2014 |
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Keywords
- Chronic villitis
- Obstetrics
- Placenta
- Premature
- Spontaneous preterm birth
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Pediatrics, Perinatology, and Child Health
Cite this
Bridging the gaps between the histopathological and demographic risk factors of preterm birth in a Unique Miami inner-city population. / Veerapen, Muthu Kumar; Pelaez, Liset; Potter, JoNell E; Duthely, Lunthita; Birusingh, Rhea; Rampersaud, Evadnie; Bodamer, Olaf A.; Rodriguez, Maria.
In: Fetal and Pediatric Pathology, Vol. 33, No. 4, 01.01.2014, p. 226-233.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Bridging the gaps between the histopathological and demographic risk factors of preterm birth in a Unique Miami inner-city population
AU - Veerapen, Muthu Kumar
AU - Pelaez, Liset
AU - Potter, JoNell E
AU - Duthely, Lunthita
AU - Birusingh, Rhea
AU - Rampersaud, Evadnie
AU - Bodamer, Olaf A.
AU - Rodriguez, Maria
PY - 2014/1/1
Y1 - 2014/1/1
N2 - We aim to identify the link between placental histological findings and obstetric reports to determine possible risk factors of spontaneous preterm birth (SPTB). We prospectively ascertained birth records and outcomes from all deliveries in our hospital in 1 year. Records were used to determine and stratify for either full-term or preterm spontaneous or indicated (I)" deliveries. We analyzed for risk factor association using χ2 tests and common odds ratio estimates (SPSS v21.0). Our cohort totaled 6088 deliveries: 236 IPTB, 43 SPTB, and 5809 term births. Largely Hispanic, we determined race, parity, prenatal care access, preeclampsia, gestational diabetes, and BMI to be highly associated with SPTB (p < 0.01). Histologically, placentas of women with SPTB were twice as likely to have chronic villitis. We found that chronic villitis is associated with SPTB. Results of this study can be used in increasing the understanding of SPTB.
AB - We aim to identify the link between placental histological findings and obstetric reports to determine possible risk factors of spontaneous preterm birth (SPTB). We prospectively ascertained birth records and outcomes from all deliveries in our hospital in 1 year. Records were used to determine and stratify for either full-term or preterm spontaneous or indicated (I)" deliveries. We analyzed for risk factor association using χ2 tests and common odds ratio estimates (SPSS v21.0). Our cohort totaled 6088 deliveries: 236 IPTB, 43 SPTB, and 5809 term births. Largely Hispanic, we determined race, parity, prenatal care access, preeclampsia, gestational diabetes, and BMI to be highly associated with SPTB (p < 0.01). Histologically, placentas of women with SPTB were twice as likely to have chronic villitis. We found that chronic villitis is associated with SPTB. Results of this study can be used in increasing the understanding of SPTB.
KW - Chronic villitis
KW - Obstetrics
KW - Placenta
KW - Premature
KW - Spontaneous preterm birth
UR - http://www.scopus.com/inward/record.url?scp=84903156960&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84903156960&partnerID=8YFLogxK
U2 - 10.3109/15513815.2014.913749
DO - 10.3109/15513815.2014.913749
M3 - Article
C2 - 24833307
AN - SCOPUS:84903156960
VL - 33
SP - 226
EP - 233
JO - Fetal and Pediatric Pathology
JF - Fetal and Pediatric Pathology
SN - 1551-3815
IS - 4
ER -