Breath-hold spin-echo MR imaging for evaluation of dynamic enhancement of native and treated hepatocellular carcinoma after intravenous Gd-DTPA administration

Riccardo Lencioni; Mario Mascalchi; Alessandro Paolicchi; Virna Zampa

doi:10.1007/BF01771700

Breath-hold spin-echo MR imaging for evaluation of dynamic enhancement of native and treated hepatocellular carcinoma after intravenous Gd-DTPA administration

Riccardo Lencioni, Mario Mascalchi, Alessandro Paolicchi, Virna Zampa

Radiology

Research output: Contribution to journal › Article

6 Scopus citations

Abstract

Using a simple modification of a standard spin-echo sequence which enables acquisition of three breath-hold images in 15 s, dynamic enhancement of 30 histologically proven hepatocellular carcinomas (17 native tumors, 6 completely necrotic tumors after nonsurgical treatments, and 7 tumors with viable and necrotic portions) after intravenous injection of gadolinium-DTPA was evaluated. Native hepatocellular carcinomas and viable portions in treated nodules showed elective enhancement in images obtained 40 s after contrast injection. Contrast between these lesions and the normal liver decreased thereafter. No contrast uptake was seen in entirely necrotic nodules and necrotic portions of treated nodules. Because of the capability to demonstrate the elective arterial blood supply typical of hepatocellular carcinoma, breath-hold T₁-weighted spin-echo sequence should replace conventional T₁-weighted images for the evaluation of intravenously administered gadolinium-DTPA enhancement of this tumor before and after nonsurgical treatments.

Original language	English (US)
Pages (from-to)	151-156
Number of pages	6
Journal	MAGMA Magnetic Resonance Materials in Physics, Biology, and Medicine
Volume	3
Issue number	3-4
DOIs	https://doi.org/10.1007/BF01771700
State	Published - Sep 1 1995

Keywords

dynamic MR imaging
gadolinium-DTPA
hepatic tumors

ASJC Scopus subject areas

Biophysics
Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging

Access to Document

10.1007/BF01771700

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Lencioni, R., Mascalchi, M., Paolicchi, A., & Zampa, V. (1995). Breath-hold spin-echo MR imaging for evaluation of dynamic enhancement of native and treated hepatocellular carcinoma after intravenous Gd-DTPA administration. MAGMA Magnetic Resonance Materials in Physics, Biology, and Medicine, 3(3-4), 151-156. https://doi.org/10.1007/BF01771700

Breath-hold spin-echo MR imaging for evaluation of dynamic enhancement of native and treated hepatocellular carcinoma after intravenous Gd-DTPA administration. / Lencioni, Riccardo; Mascalchi, Mario; Paolicchi, Alessandro; Zampa, Virna.

In: MAGMA Magnetic Resonance Materials in Physics, Biology, and Medicine, Vol. 3, No. 3-4, 01.09.1995, p. 151-156.

Research output: Contribution to journal › Article

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