Abstract
Using a simple modification of a standard spin-echo sequence which enables acquisition of three breath-hold images in 15 s, dynamic enhancement of 30 histologically proven hepatocellular carcinomas (17 native tumors, 6 completely necrotic tumors after nonsurgical treatments, and 7 tumors with viable and necrotic portions) after intravenous injection of gadolinium-DTPA was evaluated. Native hepatocellular carcinomas and viable portions in treated nodules showed elective enhancement in images obtained 40 s after contrast injection. Contrast between these lesions and the normal liver decreased thereafter. No contrast uptake was seen in entirely necrotic nodules and necrotic portions of treated nodules. Because of the capability to demonstrate the elective arterial blood supply typical of hepatocellular carcinoma, breath-hold T1-weighted spin-echo sequence should replace conventional T1-weighted images for the evaluation of intravenously administered gadolinium-DTPA enhancement of this tumor before and after nonsurgical treatments.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 151-156 |
| Number of pages | 6 |
| Journal | Magnetic Resonance Materials in Physics, Biology and Medicine |
| Volume | 3 |
| Issue number | 3-4 |
| DOIs | |
| State | Published - Sep 1995 |
| Externally published | Yes |
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Keywords
- dynamic MR imaging
- gadolinium-DTPA
- hepatic tumors
ASJC Scopus subject areas
- Genetics
- Biophysics
Cite this
Breath-hold spin-echo MR imaging for evaluation of dynamic enhancement of native and treated hepatocellular carcinoma after intravenous Gd-DTPA administration. / Lencioni, Riccardo; Mascalchi, Mario; Paolicchi, Alessandro; Zampa, Virna.
In: Magnetic Resonance Materials in Physics, Biology and Medicine, Vol. 3, No. 3-4, 09.1995, p. 151-156.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Breath-hold spin-echo MR imaging for evaluation of dynamic enhancement of native and treated hepatocellular carcinoma after intravenous Gd-DTPA administration
AU - Lencioni, Riccardo
AU - Mascalchi, Mario
AU - Paolicchi, Alessandro
AU - Zampa, Virna
PY - 1995/9
Y1 - 1995/9
N2 - Using a simple modification of a standard spin-echo sequence which enables acquisition of three breath-hold images in 15 s, dynamic enhancement of 30 histologically proven hepatocellular carcinomas (17 native tumors, 6 completely necrotic tumors after nonsurgical treatments, and 7 tumors with viable and necrotic portions) after intravenous injection of gadolinium-DTPA was evaluated. Native hepatocellular carcinomas and viable portions in treated nodules showed elective enhancement in images obtained 40 s after contrast injection. Contrast between these lesions and the normal liver decreased thereafter. No contrast uptake was seen in entirely necrotic nodules and necrotic portions of treated nodules. Because of the capability to demonstrate the elective arterial blood supply typical of hepatocellular carcinoma, breath-hold T1-weighted spin-echo sequence should replace conventional T1-weighted images for the evaluation of intravenously administered gadolinium-DTPA enhancement of this tumor before and after nonsurgical treatments.
AB - Using a simple modification of a standard spin-echo sequence which enables acquisition of three breath-hold images in 15 s, dynamic enhancement of 30 histologically proven hepatocellular carcinomas (17 native tumors, 6 completely necrotic tumors after nonsurgical treatments, and 7 tumors with viable and necrotic portions) after intravenous injection of gadolinium-DTPA was evaluated. Native hepatocellular carcinomas and viable portions in treated nodules showed elective enhancement in images obtained 40 s after contrast injection. Contrast between these lesions and the normal liver decreased thereafter. No contrast uptake was seen in entirely necrotic nodules and necrotic portions of treated nodules. Because of the capability to demonstrate the elective arterial blood supply typical of hepatocellular carcinoma, breath-hold T1-weighted spin-echo sequence should replace conventional T1-weighted images for the evaluation of intravenously administered gadolinium-DTPA enhancement of this tumor before and after nonsurgical treatments.
KW - dynamic MR imaging
KW - gadolinium-DTPA
KW - hepatic tumors
UR - http://www.scopus.com/inward/record.url?scp=0029589202&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029589202&partnerID=8YFLogxK
U2 - 10.1007/BF01771700
DO - 10.1007/BF01771700
M3 - Article
C2 - 8749733
AN - SCOPUS:0029589202
VL - 3
SP - 151
EP - 156
JO - Magnetic Resonance Materials in Physics, Biology, and Medicine
JF - Magnetic Resonance Materials in Physics, Biology, and Medicine
SN - 1352-8661
IS - 3-4
ER -