Breast cyst simulating metastases on iodine-131 imaging in thyroid carcinoma

Anton Serafini, George Sfakianakis, Michalakis Georgiou, James Morris

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


False-positive radioiodine uptake has been reported in many organ systems. We describe a female patient who had mixed papillary and follicular thyroid carcinoma, and on radioiodine total-body imaging demonstrated focal, lower-right chest uptake. Special prone imaging with the right breast dependent proved that the uptake was inside the right breast. Review of a recent breast ultrasound and mammograms showed this uptake to correspond to a large breast cyst. It is known that 131I breast uptake may be functional within the mammary gland. In this patient, it was due to retention within the cyst after the background activity decreased. Knowledge of this phenomenon may improve the interpretation of total-body 131INa studies.

Original languageEnglish (US)
Pages (from-to)1910-1912
Number of pages3
JournalJournal of Nuclear Medicine
Issue number11
StatePublished - Nov 1998


  • Breast cyst
  • Iodine-131
  • Radioiodine imaging
  • Thyroid carcinoma

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology


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