Breast cancer imaging and tomography using a hand-held optical imager

Sarah J. Erickson, Manuela Roman, Jean Gonzalez, Richard Kiszonas, Cristina Lopez-Penalver, Anuradha Godavarty

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Hand-held optical imaging devices are currently developed by several research groups as a noninvasive and non-ionizing method towards clinical imaging of breast cancer. The devices developed to date are typically utilized towards spectroscopic imaging via reflectance-based measurements. Additionally, a couple of devices have been used to perform 3D tomography with the addition of a second modality (e.g. ultrasound). A hand-held optical device that is unique in its ability to perform rapid 2D imaging and 3D tomography (without the use of a second modality) has been developed in our Optical Imaging laboratory. Herein, diffuse optical imaging studies are performed in breast cancer subjects. For these studies, the subject lay in a recliner chair and both breast tissues were imaged with the hand-held optical device which uses 785 nm laser source and an intensified CCD camera-based detector. Preliminary results demonstrate the ability to image invasive ductal carcinoma and lymphatic spread, as compared to the patient's medical records (e.g. xray, ultrasound, MRI). Multiple imaging studies with a subject undergoing chemotherapy demonstrated the potential to monitor response to treatment. Currently, studies are carried out to tomographically determine the 3D location of the tumor(s) in breast cancer subjects using the hand-held optical device.

Original languageEnglish
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8214
DOIs
StatePublished - Jun 12 2012
EventAdvanced Biomedical and Clinical Diagnostic Systems X - San Francisco, CA, United States
Duration: Jan 22 2012Jan 24 2012

Other

OtherAdvanced Biomedical and Clinical Diagnostic Systems X
CountryUnited States
CitySan Francisco, CA
Period1/22/121/24/12

Fingerprint

Optical Devices
Image sensors
breast
Tomography
Optical Imaging
Hand
tomography
cancer
Breast Neoplasms
Imaging techniques
Optical devices
Equipment and Supplies
Ductal Carcinoma
Ultrasonics
Medical Records
Breast
Lasers
Chemotherapy
Medical imaging
X-Rays

Keywords

  • 3D tomography
  • Breast cancer
  • Clinical studies
  • Coregistration
  • Diffuse optical imaging
  • Hand-held device
  • Human subject
  • Mammography
  • Near-infrared

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Erickson, S. J., Roman, M., Gonzalez, J., Kiszonas, R., Lopez-Penalver, C., & Godavarty, A. (2012). Breast cancer imaging and tomography using a hand-held optical imager. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8214). [82140Q] https://doi.org/10.1117/12.908528

Breast cancer imaging and tomography using a hand-held optical imager. / Erickson, Sarah J.; Roman, Manuela; Gonzalez, Jean; Kiszonas, Richard; Lopez-Penalver, Cristina; Godavarty, Anuradha.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8214 2012. 82140Q.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Erickson, SJ, Roman, M, Gonzalez, J, Kiszonas, R, Lopez-Penalver, C & Godavarty, A 2012, Breast cancer imaging and tomography using a hand-held optical imager. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 8214, 82140Q, Advanced Biomedical and Clinical Diagnostic Systems X, San Francisco, CA, United States, 1/22/12. https://doi.org/10.1117/12.908528
Erickson SJ, Roman M, Gonzalez J, Kiszonas R, Lopez-Penalver C, Godavarty A. Breast cancer imaging and tomography using a hand-held optical imager. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8214. 2012. 82140Q https://doi.org/10.1117/12.908528
Erickson, Sarah J. ; Roman, Manuela ; Gonzalez, Jean ; Kiszonas, Richard ; Lopez-Penalver, Cristina ; Godavarty, Anuradha. / Breast cancer imaging and tomography using a hand-held optical imager. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8214 2012.
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