Breast cancer and depression

Wendy Somerset, Steven C. Stout, Andrew H. Miller, Dominique Musselman

Research output: Contribution to journalReview articlepeer-review

107 Scopus citations


Major depression and depressive symptoms, although commonly encountered in patients with medical illnesses, are frequently underdiagnosed and undertreated in women with breast cancer. Depression and its associated symptoms diminish quality of life, adversely affect compliance with medical therapies, and reduce survival. Treatment of depression in women with breast cancer improves their dysphoria and other depressive symptoms, enhances quality of life, and may increase longevity. In this review, studies that investigate pathophysiologic alterations in patients with cancer and comorbid depression are discussed, and the few studies on treatment of depression and related symptoms in women with breast cancer are examined.

Original languageEnglish (US)
Pages (from-to)1021-1034
Number of pages14
Issue number8
StatePublished - Jul 1 2004
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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