Abstract
Introduction: Tuberculous plaque is an uncommon and atypical presentation of CNS tuberculosis. Specific diagnosis can be difficult and this condition may not be included in the differential of intracranial lesions. Clinical case: A 64-year-old male patient with history of myelodyslastic syndrome, remote tuberculosis and dermal mycosis, who developed first-time seizure with complete symptomatic resolution. The brain MRI showed a cortico-subcortical right frontal lesion, with involvement of the dura, which enhanced with contrast agent. Biochemical and serological studies were unrevealing, but a skin biopsy showed granulomatous reaction. Antitubercu-losis treatment with four drugs was started, with clinical and radiological improvement. Conclusion: CNS tuberculosis is rare, but may occur in apparently immunocompetent patients. Tuberculous plaque should be considered in the differential diagnosis for intracranial tumors.
| Original language | Spanish |
|---|---|
| Pages (from-to) | 195-198 |
| Number of pages | 4 |
| Journal | Neurologica Argentina |
| Volume | 9 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jul 1 2017 |
| Externally published | Yes |
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Keywords
- Myelodysplastic syndrome
- Pachymeningitis
- Tuberculoma en plaque
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
Cite this
Tuberculoma cerebral en placa. Presentación atípica de tuberculosis en el sistema nervioso central. / Bessolo, Eduardo; Villate, Sebastián; Arroyo, José Alfredo; Rango, Graciela; Ortiz, Gustavo Andrés.
In: Neurologica Argentina, Vol. 9, No. 3, 01.07.2017, p. 195-198.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Tuberculoma cerebral en placa. Presentación atípica de tuberculosis en el sistema nervioso central
AU - Bessolo, Eduardo
AU - Villate, Sebastián
AU - Arroyo, José Alfredo
AU - Rango, Graciela
AU - Ortiz, Gustavo Andrés
PY - 2017/7/1
Y1 - 2017/7/1
N2 - Introduction: Tuberculous plaque is an uncommon and atypical presentation of CNS tuberculosis. Specific diagnosis can be difficult and this condition may not be included in the differential of intracranial lesions. Clinical case: A 64-year-old male patient with history of myelodyslastic syndrome, remote tuberculosis and dermal mycosis, who developed first-time seizure with complete symptomatic resolution. The brain MRI showed a cortico-subcortical right frontal lesion, with involvement of the dura, which enhanced with contrast agent. Biochemical and serological studies were unrevealing, but a skin biopsy showed granulomatous reaction. Antitubercu-losis treatment with four drugs was started, with clinical and radiological improvement. Conclusion: CNS tuberculosis is rare, but may occur in apparently immunocompetent patients. Tuberculous plaque should be considered in the differential diagnosis for intracranial tumors.
AB - Introduction: Tuberculous plaque is an uncommon and atypical presentation of CNS tuberculosis. Specific diagnosis can be difficult and this condition may not be included in the differential of intracranial lesions. Clinical case: A 64-year-old male patient with history of myelodyslastic syndrome, remote tuberculosis and dermal mycosis, who developed first-time seizure with complete symptomatic resolution. The brain MRI showed a cortico-subcortical right frontal lesion, with involvement of the dura, which enhanced with contrast agent. Biochemical and serological studies were unrevealing, but a skin biopsy showed granulomatous reaction. Antitubercu-losis treatment with four drugs was started, with clinical and radiological improvement. Conclusion: CNS tuberculosis is rare, but may occur in apparently immunocompetent patients. Tuberculous plaque should be considered in the differential diagnosis for intracranial tumors.
KW - Myelodysplastic syndrome
KW - Pachymeningitis
KW - Tuberculoma en plaque
UR - http://www.scopus.com/inward/record.url?scp=85027590307&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85027590307&partnerID=8YFLogxK
U2 - 10.1016/j.neuarg.2016.08.003
DO - 10.1016/j.neuarg.2016.08.003
M3 - Article
VL - 9
SP - 195
EP - 198
JO - Neurologia Argentina
JF - Neurologia Argentina
SN - 1853-0028
IS - 3
ER -