Brain tuberculoma brain en plaque. Atypical presentation of tuberculosis in the central nervous system

Eduardo Bessolo, Sebastián Villate, José Alfredo Arroyo, Graciela Rango, Gustavo Ortiz

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Introduction: Tuberculous plaque is an uncommon and atypical presentation of CNS tuberculosis. Specific diagnosis can be difficult and this condition may not be included in the differential of intracranial lesions. Clinical case: A 64-year-old male patient with history of myelodyslastic syndrome, remote tuberculosis and dermal mycosis, who developed first-time seizure with complete symptomatic resolution. The brain MRI showed a cortico-subcortical right frontal lesion, with involvement of the dura, which enhanced with contrast agent. Biochemical and serological studies were unrevealing, but a skin biopsy showed granulomatous reaction. Antituberculosis treatment with four drugs was started, with clinical and radiological improvement. Conclusion: CNS tuberculosis is rare, but may occur in apparently immunocompetent patients. Tuberculous plaque should be considered in the differential diagnosis for intracranial tumors.

Original languageSpanish
JournalNeurologia Argentina
StateAccepted/In press - 2016
Externally publishedYes


  • Myelodysplastic syndrome
  • Pachymeningitis
  • Tuberculoma en plaque

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this