Abstract
Magnetic resonance imaging (MRI) is a technique commonly used to detect neural abnormalities in routine clinical practice. It is perhaps less well known that the technique can be adapted to measure various anatomical and physiological features of small laboratory rodents. This review focuses on the potential of the MRI technique to image the brain of (transgenic) mouse models for neurological diseases, and aims to introduce these exciting new technological developments to the non-specialist reader.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 153-159 |
| Number of pages | 7 |
| Journal | European Journal of Human Genetics |
| Volume | 9 |
| Issue number | 3 |
| DOIs | |
| State | Published - Apr 5 2001 |
| Externally published | Yes |
Keywords
- Brain structure
- Fragile X syndrome
- Knockout mouse
- Magnetic resonance imaging
- Mental retardation
- X-linked hydrocephalus
ASJC Scopus subject areas
- Genetics(clinical)
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Cite this
Kooy, R. F., Verhoye, M., Lemmon, V., & Van Der Linden, A. (2001). Brain studies of mouse models for neurogenetic disorders using in vivo magnetic resonance imaging (MRI). European Journal of Human Genetics, 9(3), 153-159. https://doi.org/10.1038/sj.ejhg.5200606