Brain studies of mouse models for neurogenetic disorders using in vivo magnetic resonance imaging (MRI)

R. Frank Kooy, Marleen Verhoye, Vance Lemmon, Annemie Van Der Linden

Research output: Contribution to journalReview article

19 Scopus citations

Abstract

Magnetic resonance imaging (MRI) is a technique commonly used to detect neural abnormalities in routine clinical practice. It is perhaps less well known that the technique can be adapted to measure various anatomical and physiological features of small laboratory rodents. This review focuses on the potential of the MRI technique to image the brain of (transgenic) mouse models for neurological diseases, and aims to introduce these exciting new technological developments to the non-specialist reader.

Original languageEnglish (US)
Pages (from-to)153-159
Number of pages7
JournalEuropean Journal of Human Genetics
Volume9
Issue number3
DOIs
StatePublished - Apr 5 2001
Externally publishedYes

Keywords

  • Brain structure
  • Fragile X syndrome
  • Knockout mouse
  • Magnetic resonance imaging
  • Mental retardation
  • X-linked hydrocephalus

ASJC Scopus subject areas

  • Genetics(clinical)

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