Brain studies of mouse models for neurogenetic disorders using in vivo magnetic resonance imaging (MRI)

R. Frank Kooy, Marleen Verhoye, Vance Lemmon, Annemie Van Der Linden

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Magnetic resonance imaging (MRI) is a technique commonly used to detect neural abnormalities in routine clinical practice. It is perhaps less well known that the technique can be adapted to measure various anatomical and physiological features of small laboratory rodents. This review focuses on the potential of the MRI technique to image the brain of (transgenic) mouse models for neurological diseases, and aims to introduce these exciting new technological developments to the non-specialist reader.

Original languageEnglish
Pages (from-to)153-159
Number of pages7
JournalEuropean Journal of Human Genetics
Volume9
Issue number3
DOIs
StatePublished - Apr 5 2001
Externally publishedYes

Fingerprint

Neurological Models
Magnetic Resonance Imaging
Brain
Transgenic Mice
Rodentia

Keywords

  • Brain structure
  • Fragile X syndrome
  • Knockout mouse
  • Magnetic resonance imaging
  • Mental retardation
  • X-linked hydrocephalus

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

Brain studies of mouse models for neurogenetic disorders using in vivo magnetic resonance imaging (MRI). / Kooy, R. Frank; Verhoye, Marleen; Lemmon, Vance; Van Der Linden, Annemie.

In: European Journal of Human Genetics, Vol. 9, No. 3, 05.04.2001, p. 153-159.

Research output: Contribution to journalArticle

Kooy, R. Frank ; Verhoye, Marleen ; Lemmon, Vance ; Van Der Linden, Annemie. / Brain studies of mouse models for neurogenetic disorders using in vivo magnetic resonance imaging (MRI). In: European Journal of Human Genetics. 2001 ; Vol. 9, No. 3. pp. 153-159.
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