Abstract
Magnetic resonance imaging (MRI) is a technique commonly used to detect neural abnormalities in routine clinical practice. It is perhaps less well known that the technique can be adapted to measure various anatomical and physiological features of small laboratory rodents. This review focuses on the potential of the MRI technique to image the brain of (transgenic) mouse models for neurological diseases, and aims to introduce these exciting new technological developments to the non-specialist reader.
| Original language | English |
|---|---|
| Pages (from-to) | 153-159 |
| Number of pages | 7 |
| Journal | European Journal of Human Genetics |
| Volume | 9 |
| Issue number | 3 |
| DOIs | |
| State | Published - Apr 5 2001 |
| Externally published | Yes |
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Keywords
- Brain structure
- Fragile X syndrome
- Knockout mouse
- Magnetic resonance imaging
- Mental retardation
- X-linked hydrocephalus
ASJC Scopus subject areas
- Genetics(clinical)
Cite this
Brain studies of mouse models for neurogenetic disorders using in vivo magnetic resonance imaging (MRI). / Kooy, R. Frank; Verhoye, Marleen; Lemmon, Vance; Van Der Linden, Annemie.
In: European Journal of Human Genetics, Vol. 9, No. 3, 05.04.2001, p. 153-159.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Brain studies of mouse models for neurogenetic disorders using in vivo magnetic resonance imaging (MRI)
AU - Kooy, R. Frank
AU - Verhoye, Marleen
AU - Lemmon, Vance
AU - Van Der Linden, Annemie
PY - 2001/4/5
Y1 - 2001/4/5
N2 - Magnetic resonance imaging (MRI) is a technique commonly used to detect neural abnormalities in routine clinical practice. It is perhaps less well known that the technique can be adapted to measure various anatomical and physiological features of small laboratory rodents. This review focuses on the potential of the MRI technique to image the brain of (transgenic) mouse models for neurological diseases, and aims to introduce these exciting new technological developments to the non-specialist reader.
AB - Magnetic resonance imaging (MRI) is a technique commonly used to detect neural abnormalities in routine clinical practice. It is perhaps less well known that the technique can be adapted to measure various anatomical and physiological features of small laboratory rodents. This review focuses on the potential of the MRI technique to image the brain of (transgenic) mouse models for neurological diseases, and aims to introduce these exciting new technological developments to the non-specialist reader.
KW - Brain structure
KW - Fragile X syndrome
KW - Knockout mouse
KW - Magnetic resonance imaging
KW - Mental retardation
KW - X-linked hydrocephalus
UR - http://www.scopus.com/inward/record.url?scp=0035076388&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035076388&partnerID=8YFLogxK
U2 - 10.1038/sj.ejhg.5200606
DO - 10.1038/sj.ejhg.5200606
M3 - Article
VL - 9
SP - 153
EP - 159
JO - European Journal of Human Genetics
JF - European Journal of Human Genetics
SN - 1018-4813
IS - 3
ER -