Brachytherapy in the treatment of recurrent solitary brain metastases

D. O. Heros, D. L. Kasdon, M. Chun, R. G. Selker

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Conventional therapy for solitary brain metastases includes radiotherapy and surgical resection in selected cases. Often, however, the metastasis recurs and limits the quality of life and survival of the patient. Once the metastasis recurs, therapeutic options are limited. Brachytherapy delivers a high total dose of radiation to a localized area, allowing reirradiation at the time of recurrence. Three patients with recurrent brain metastases treated with iridium-192 implants are presented; two of these patients had breast carcinoma and one had malignant melanoma. The implants allowed long term survival in the two patients with recurrent metastatic breast carcinoma. Unfortunately, the patient with melanoma did not respond to the brachytherapy and died within 7 months of implantation. The approaches to treatment to metastatic brain tumors and the rationale for using brachytherapy are discussed.

Original languageEnglish (US)
Pages (from-to)733-737
Number of pages5
JournalNeurosurgery
Volume23
Issue number6
DOIs
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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