Bovine spongiform encephalopathy - Some surprises for biochemists

Peter N. Campbell, William J. Whelan

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Bovine Spongiform Encephalopathy (BSE) is typical of the dementias that affect both animals and man; Scrapie in sheep, Creutzfeldt-Jakob disease in man. Global efforts have been made to determine the nature of the active agents in these diseases. At present the 'protein only hypothesis' of Prusiner holds. It was a surprise that a protein could per se be the active agent but other surprises for our traditional teaching of biochemistry arose. These are explained in a brief summary of our present understanding of the biochemistry of the active agents that cause the diseases.

Original languageEnglish
Pages (from-to)273-276
Number of pages4
JournalIUBMB Life
Volume57
Issue number4-5
DOIs
StatePublished - Apr 1 2005

Fingerprint

Bovine Spongiform Encephalopathy
Biochemistry
Scrapie
Creutzfeldt-Jakob Syndrome
Dementia
Sheep
Teaching
Proteins
Animals

Keywords

  • Bovine Spongiform Encephalopathy
  • Prions
  • Scrapie

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

Cite this

Bovine spongiform encephalopathy - Some surprises for biochemists. / Campbell, Peter N.; Whelan, William J.

In: IUBMB Life, Vol. 57, No. 4-5, 01.04.2005, p. 273-276.

Research output: Contribution to journalArticle

Campbell, Peter N. ; Whelan, William J. / Bovine spongiform encephalopathy - Some surprises for biochemists. In: IUBMB Life. 2005 ; Vol. 57, No. 4-5. pp. 273-276.
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