Bone transplantation and human immunodeficiency virus: An estimate of risk of acquired immunodeficiency syndrome (AIDS)

B. E. Buck, Theodore Malinin, Mark Brown

Research output: Contribution to journalArticle

500 Citations (Scopus)

Abstract

The possibility of transplanting a bone allograft from a donor infected with human immunodeficiency virus (HIV) is remote, provided there is a combination of rigorous donor selection and exclusion, screening for the HIV antigen and antibody, and histopathologic studies of donor tissues. The chance of obtaining a bone allograft from an HIV-infected donor who failed to be excluded by the above techniques is calculated to be one in well over a million, using average estimates. On the other hand, if adequate precautions are not taken (for example, by testing only for antibodies to HIV), the risk might be as high as one in 161.

Original languageEnglish
Pages (from-to)129-136
Number of pages8
JournalClinical Orthopaedics and Related Research
Issue number240
StatePublished - Jan 1 1989

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Bone Transplantation
Acquired Immunodeficiency Syndrome
HIV
Donor Selection
Allografts
Bone and Bones
Antibodies
Tissue Donors
Antigens

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

Cite this

Bone transplantation and human immunodeficiency virus : An estimate of risk of acquired immunodeficiency syndrome (AIDS). / Buck, B. E.; Malinin, Theodore; Brown, Mark.

In: Clinical Orthopaedics and Related Research, No. 240, 01.01.1989, p. 129-136.

Research output: Contribution to journalArticle

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