Bone Tissue Engineering via Carbon-Based Nanomaterials

Zhili Peng, Tianshu Zhao, Yiqun Zhou, Shanghao Li, Jiaojiao Li, Roger M. Leblanc

Research output: Contribution to journalReview article

Abstract

Bone tissue engineering (BTE) has received significant attention due to its enormous potential in treating critical-sized bone defects and related diseases. Traditional materials such as metals, ceramics, and polymers have been widely applied as BTE scaffolds; however, their clinical applications have been rather limited due to various considerations. Recently, carbon-based nanomaterials attract significant interests for their applications as BTE scaffolds due to their superior properties, including excellent mechanical strength, large surface area, tunable surface functionalities, high biocompatibility as well as abundant and inexpensive nature. In this article, recent studies and advancements on the use of carbon-based nanomaterials with different dimensions such as graphene and its derivatives, carbon nanotubes, and carbon dots, for BTE are reviewed. Current challenges of carbon-based nanomaterials for BTE and future trends in BTE scaffolds development are also highlighted and discussed.

Original languageEnglish (US)
Article number1901495
JournalAdvanced Healthcare Materials
DOIs
StateAccepted/In press - Jan 1 2020

    Fingerprint

Keywords

  • bone tissue engineering
  • carbon dots
  • carbon nanomaterials
  • graphene oxide
  • osteogenic differentiation

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Pharmaceutical Science

Cite this