Bone allograft in limb reconstruction

Melissa M. Kounine, Aditya V. Maheshwari, J. David Pitcher, H. Thomas Temple

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


PURPOSE OF REVIEW: The aim of this article is to review the recent literature regarding bone allograft, placing it into perspective with the previous literature and to inform surgeons and clinicians of important changes in the practice of tissue banking and limb reconstruction with bone allograft tissues. RECENT FINDINGS: The emphasis in the use of allografts is moving more towards increasing responsibility for the individual surgeon using bone allografts along with knowledge of good tissue banking practices and federal regulations. Improved surgical techniques including tissue attachment and sized allograft matching has improved long-term results. Improved radiologic techniques are being applied to the evaluation of bone allografting. Disease transmission, although rare following current protocols, continues to be a major concern that attracts public attention. Use of allografts in children has shown long-term complications compromising durability of the reconstruction. SUMMARY: The surgeon's responsibility when using bone allograft spans the breadth of federal regulations, tissue banking practices, surgical techniques, radiologic evaluation, infectious disease, anticipation and proper handling of complications, and public education.

Original languageEnglish (US)
Pages (from-to)579-589
Number of pages11
JournalCurrent Opinion in Orthopaedics
Issue number6
StatePublished - Nov 2007
Externally publishedYes


  • Bone allograft
  • Limb reconstruction
  • Tissue banking

ASJC Scopus subject areas

  • Surgery


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