Abstract
Objective: To determine optimal threshold values for body mass index (BMI) and waist circumference (WC) for detecting cardiovascular disease (CVD) risk (as defined with ≥3 CVD risk factors [RFs]) in adolescents. Study design: The 1999-2004 National Health and Nutrition Examination Surveys (NHANES) cross-sectional data for 12- to 19-year-old adolescents (n = 2581) was analyzed. Main outcome measures were ≥3 age-adjusted CVD RFs (high- and low-density lipoprotein cholesterol level, triglyceride level, glucose level, insulin level, and systolic and diastolic blood pressure). The presence of ≥3 RFs was predicted from age- and sex-adjusted BMI and WC values with receiver operating characteristics analyses. Results: The proportion of adolescents at risk for ≥3 RFs ranged from 17% to 19%. Both BMI and WC had good diagnostic accuracy, ranging from 0.73 to 0.83, and good sensitivity and specificity, ranging from 0.68 to 0.77. The BMI cutoff points ranged from 19.5 to 25.0 kg/m2 for boys and from 19.4 to 27.0 kg/m2 for girls, and WC cutoff points ranged from 66.8 to 87.5 cm for boys and from 71.5 to 87.2 cm for girls. Conclusions: Age-, sex-, and ethnicity/race-specific threshold values for BMI and WC may have significant clinical usefulness in identifying adolescents and teenagers at risk for later CVD onset.
| Original language | English |
|---|---|
| Journal | Journal of Pediatrics |
| Volume | 153 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 1 2008 |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Body Mass Index, Waist Circumference, and Cardiovascular Risk Factors in Adolescents. / Messiah, Sarah; Arheart, Kristopher; Lipshultz, Steven E; Miller, Tracie L.
In: Journal of Pediatrics, Vol. 153, No. 6, 01.12.2008.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Body Mass Index, Waist Circumference, and Cardiovascular Risk Factors in Adolescents
AU - Messiah, Sarah
AU - Arheart, Kristopher
AU - Lipshultz, Steven E
AU - Miller, Tracie L
PY - 2008/12/1
Y1 - 2008/12/1
N2 - Objective: To determine optimal threshold values for body mass index (BMI) and waist circumference (WC) for detecting cardiovascular disease (CVD) risk (as defined with ≥3 CVD risk factors [RFs]) in adolescents. Study design: The 1999-2004 National Health and Nutrition Examination Surveys (NHANES) cross-sectional data for 12- to 19-year-old adolescents (n = 2581) was analyzed. Main outcome measures were ≥3 age-adjusted CVD RFs (high- and low-density lipoprotein cholesterol level, triglyceride level, glucose level, insulin level, and systolic and diastolic blood pressure). The presence of ≥3 RFs was predicted from age- and sex-adjusted BMI and WC values with receiver operating characteristics analyses. Results: The proportion of adolescents at risk for ≥3 RFs ranged from 17% to 19%. Both BMI and WC had good diagnostic accuracy, ranging from 0.73 to 0.83, and good sensitivity and specificity, ranging from 0.68 to 0.77. The BMI cutoff points ranged from 19.5 to 25.0 kg/m2 for boys and from 19.4 to 27.0 kg/m2 for girls, and WC cutoff points ranged from 66.8 to 87.5 cm for boys and from 71.5 to 87.2 cm for girls. Conclusions: Age-, sex-, and ethnicity/race-specific threshold values for BMI and WC may have significant clinical usefulness in identifying adolescents and teenagers at risk for later CVD onset.
AB - Objective: To determine optimal threshold values for body mass index (BMI) and waist circumference (WC) for detecting cardiovascular disease (CVD) risk (as defined with ≥3 CVD risk factors [RFs]) in adolescents. Study design: The 1999-2004 National Health and Nutrition Examination Surveys (NHANES) cross-sectional data for 12- to 19-year-old adolescents (n = 2581) was analyzed. Main outcome measures were ≥3 age-adjusted CVD RFs (high- and low-density lipoprotein cholesterol level, triglyceride level, glucose level, insulin level, and systolic and diastolic blood pressure). The presence of ≥3 RFs was predicted from age- and sex-adjusted BMI and WC values with receiver operating characteristics analyses. Results: The proportion of adolescents at risk for ≥3 RFs ranged from 17% to 19%. Both BMI and WC had good diagnostic accuracy, ranging from 0.73 to 0.83, and good sensitivity and specificity, ranging from 0.68 to 0.77. The BMI cutoff points ranged from 19.5 to 25.0 kg/m2 for boys and from 19.4 to 27.0 kg/m2 for girls, and WC cutoff points ranged from 66.8 to 87.5 cm for boys and from 71.5 to 87.2 cm for girls. Conclusions: Age-, sex-, and ethnicity/race-specific threshold values for BMI and WC may have significant clinical usefulness in identifying adolescents and teenagers at risk for later CVD onset.
UR - http://www.scopus.com/inward/record.url?scp=56049125259&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=56049125259&partnerID=8YFLogxK
U2 - 10.1016/j.jpeds.2008.06.013
DO - 10.1016/j.jpeds.2008.06.013
M3 - Article
C2 - 18675434
AN - SCOPUS:56049125259
VL - 153
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 6
ER -