TY - JOUR
T1 - Bloodstream infection risk, incidence, and deaths for hospitalized patients during coronavirus disease pandemic
AU - Shukla, Bhavarth S.
AU - Warde, Prem R.
AU - Knott, Eric
AU - Arenas, Sebastian
AU - Pronty, Darryl
AU - Ramirez, Reinaldo
AU - Rego, Arely
AU - Levy, Miriam
AU - Zak, Martin
AU - Parekh, Dipen J.
AU - Ferreira, Tanira
AU - Gershengorn, Hayley B.
N1 - Publisher Copyright:
© 2021 Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2021/10
Y1 - 2021/10
N2 - Hospital-acquired infections are emerging major concurrent conditions during the coronavirus disease (COVID-19) pandemic. We conducted a retrospective review of hospitalizations during March-October 2020 of adults tested by reverse transcription PCR for severe acute respiratory syndrome coronavirus 2. We evaluated associations of COVID-19 diagnosis with risk for laboratory-confi rmed bloodstream infections (LCBIs, primary outcome), time to LCBI, and risk for death by using logistic and competing risks regression with adjustment for relevant covariates. A total of 10,848 patients were included in the analysis: 918 (8.5%) were given a diagnosis of COVID-19, and 232 (2.1%) had LCBIs during their hospitalization. Of these patients, 58 (25%) were classifi ed as having central line-associated bloodstream infections. After adjusting for covariates, COVID-19-positive status was associated with higher risk for LCBI and death. Reinforcement of infection control practices should be implemented in COVID-19 wards, and review of superiority and inferiority ranking methods by National Healthcare Safety Network criteria might be needed.
AB - Hospital-acquired infections are emerging major concurrent conditions during the coronavirus disease (COVID-19) pandemic. We conducted a retrospective review of hospitalizations during March-October 2020 of adults tested by reverse transcription PCR for severe acute respiratory syndrome coronavirus 2. We evaluated associations of COVID-19 diagnosis with risk for laboratory-confi rmed bloodstream infections (LCBIs, primary outcome), time to LCBI, and risk for death by using logistic and competing risks regression with adjustment for relevant covariates. A total of 10,848 patients were included in the analysis: 918 (8.5%) were given a diagnosis of COVID-19, and 232 (2.1%) had LCBIs during their hospitalization. Of these patients, 58 (25%) were classifi ed as having central line-associated bloodstream infections. After adjusting for covariates, COVID-19-positive status was associated with higher risk for LCBI and death. Reinforcement of infection control practices should be implemented in COVID-19 wards, and review of superiority and inferiority ranking methods by National Healthcare Safety Network criteria might be needed.
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U2 - 10.3201/eid2710.210538
DO - 10.3201/eid2710.210538
M3 - Article
C2 - 34352195
AN - SCOPUS:85115357946
VL - 27
SP - 2588
EP - 2594
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
SN - 1080-6040
IS - 10
ER -