Abstract
Background. Cardiac revascularization on a beating heart avoids the side effects of cardiopulmonary bypass (eg, neurologic injury, hemodilution, and coagulopathy). We examined perioperative bleeding and use of blood products during coronary artery bypass grafting using either on-pump or off-pump techniques. Method. The charts of 126 patients who had coronary artery bypass grafting were reviewed. Data from 66 patients revascularized off pump and 60 patients with cardiopulmonary bypass (on pump) were analyzed using unpaired Student's t test. Results. Average age was 62.5 years in either group. More patients received heparin preoperatively in the off-pump group that resulted in mild elevation of preoperative partial thromboplastin time and activated clotting time (40.4 ± 2.9 seconds and 150.1 ± 5.3 seconds, respectively). However, the off-pump group had less perioperative (intraoperative or postoperative) bleeding (2312 ± 212 mL versus 3251 ± 155 mL, p < 0.05) and required fewer blood products compared with the on- pump group. Hemoglobin and platelets decreased more in the conventional on-pump group. Conclusions. Avoiding cardiopulmonary bypass decreases perioperative bleeding and, consequently, reduces the use of blood products after coronary artery bypass grafting, which might result in fewer transfusion-related complications.
| Original language | English |
|---|---|
| Pages (from-to) | 1640-1643 |
| Number of pages | 4 |
| Journal | Annals of Thoracic Surgery |
| Volume | 68 |
| Issue number | 5 |
| DOIs | |
| State | Published - Nov 1 1999 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Surgery
Cite this
Blood product use in cardiac revascularization : Comparison of on- and off-pump techniques. / Nader, Nader D.; Khadra, Wiam Z.; Reich, Neal T.; Bacon, Douglas R.; Salerno, Tomas; Panos, Anthony L.
In: Annals of Thoracic Surgery, Vol. 68, No. 5, 01.11.1999, p. 1640-1643.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Blood product use in cardiac revascularization
T2 - Comparison of on- and off-pump techniques
AU - Nader, Nader D.
AU - Khadra, Wiam Z.
AU - Reich, Neal T.
AU - Bacon, Douglas R.
AU - Salerno, Tomas
AU - Panos, Anthony L.
PY - 1999/11/1
Y1 - 1999/11/1
N2 - Background. Cardiac revascularization on a beating heart avoids the side effects of cardiopulmonary bypass (eg, neurologic injury, hemodilution, and coagulopathy). We examined perioperative bleeding and use of blood products during coronary artery bypass grafting using either on-pump or off-pump techniques. Method. The charts of 126 patients who had coronary artery bypass grafting were reviewed. Data from 66 patients revascularized off pump and 60 patients with cardiopulmonary bypass (on pump) were analyzed using unpaired Student's t test. Results. Average age was 62.5 years in either group. More patients received heparin preoperatively in the off-pump group that resulted in mild elevation of preoperative partial thromboplastin time and activated clotting time (40.4 ± 2.9 seconds and 150.1 ± 5.3 seconds, respectively). However, the off-pump group had less perioperative (intraoperative or postoperative) bleeding (2312 ± 212 mL versus 3251 ± 155 mL, p < 0.05) and required fewer blood products compared with the on- pump group. Hemoglobin and platelets decreased more in the conventional on-pump group. Conclusions. Avoiding cardiopulmonary bypass decreases perioperative bleeding and, consequently, reduces the use of blood products after coronary artery bypass grafting, which might result in fewer transfusion-related complications.
AB - Background. Cardiac revascularization on a beating heart avoids the side effects of cardiopulmonary bypass (eg, neurologic injury, hemodilution, and coagulopathy). We examined perioperative bleeding and use of blood products during coronary artery bypass grafting using either on-pump or off-pump techniques. Method. The charts of 126 patients who had coronary artery bypass grafting were reviewed. Data from 66 patients revascularized off pump and 60 patients with cardiopulmonary bypass (on pump) were analyzed using unpaired Student's t test. Results. Average age was 62.5 years in either group. More patients received heparin preoperatively in the off-pump group that resulted in mild elevation of preoperative partial thromboplastin time and activated clotting time (40.4 ± 2.9 seconds and 150.1 ± 5.3 seconds, respectively). However, the off-pump group had less perioperative (intraoperative or postoperative) bleeding (2312 ± 212 mL versus 3251 ± 155 mL, p < 0.05) and required fewer blood products compared with the on- pump group. Hemoglobin and platelets decreased more in the conventional on-pump group. Conclusions. Avoiding cardiopulmonary bypass decreases perioperative bleeding and, consequently, reduces the use of blood products after coronary artery bypass grafting, which might result in fewer transfusion-related complications.
UR - http://www.scopus.com/inward/record.url?scp=0032709832&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032709832&partnerID=8YFLogxK
U2 - 10.1016/S0003-4975(99)00827-9
DO - 10.1016/S0003-4975(99)00827-9
M3 - Article
C2 - 10585034
AN - SCOPUS:0032709832
VL - 68
SP - 1640
EP - 1643
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
SN - 0003-4975
IS - 5
ER -