Abstract
The relation of blood pressure to fasting (basal) insulin and glycosylated hemoglobin (hemoglobin A1) was examined in 248 nondiabetic subjects (137 women and 111 men). None of the subjects was taking antihypertensive medication. There were statistically significant associations of systolic and diastolic blood pressure with insulin levels (r = 0.24, p <0.01; r = 0.30, p <0.01) and hemoglobin A1 levels (r = 0.28, p <0.001; r = 0.22, p <0.05) in women. These blood pressure indexes were also related to insulin levels in men (r = 0.23, p <0.05; r = 0.02, p <0.05). In a multiple regression analysis, the association between blood pressure and insulin level was diminished with an allowance for adiposity; however, it remained statistically significant. These data indicate that blood pressure is related to insulin levels in nondiabetic subjects and suggest that insulin may be a physiologic determinant of blood pressure.
| Original language | English |
|---|---|
| Pages (from-to) | 861-864 |
| Number of pages | 4 |
| Journal | The American Journal of Medicine |
| Volume | 80 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jan 1 1986 |
Fingerprint
ASJC Scopus subject areas
- Nursing(all)
Cite this
Blood pressure, insulin, and glycemia in nondiabetic subjects. / Fournier, Arthur M.; Gadia, Maria T.; Kubrusly, Denise B.; Skyler, Jay S; Sosenko, Jay M.
In: The American Journal of Medicine, Vol. 80, No. 5, 01.01.1986, p. 861-864.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Blood pressure, insulin, and glycemia in nondiabetic subjects
AU - Fournier, Arthur M.
AU - Gadia, Maria T.
AU - Kubrusly, Denise B.
AU - Skyler, Jay S
AU - Sosenko, Jay M
PY - 1986/1/1
Y1 - 1986/1/1
N2 - The relation of blood pressure to fasting (basal) insulin and glycosylated hemoglobin (hemoglobin A1) was examined in 248 nondiabetic subjects (137 women and 111 men). None of the subjects was taking antihypertensive medication. There were statistically significant associations of systolic and diastolic blood pressure with insulin levels (r = 0.24, p <0.01; r = 0.30, p <0.01) and hemoglobin A1 levels (r = 0.28, p <0.001; r = 0.22, p <0.05) in women. These blood pressure indexes were also related to insulin levels in men (r = 0.23, p <0.05; r = 0.02, p <0.05). In a multiple regression analysis, the association between blood pressure and insulin level was diminished with an allowance for adiposity; however, it remained statistically significant. These data indicate that blood pressure is related to insulin levels in nondiabetic subjects and suggest that insulin may be a physiologic determinant of blood pressure.
AB - The relation of blood pressure to fasting (basal) insulin and glycosylated hemoglobin (hemoglobin A1) was examined in 248 nondiabetic subjects (137 women and 111 men). None of the subjects was taking antihypertensive medication. There were statistically significant associations of systolic and diastolic blood pressure with insulin levels (r = 0.24, p <0.01; r = 0.30, p <0.01) and hemoglobin A1 levels (r = 0.28, p <0.001; r = 0.22, p <0.05) in women. These blood pressure indexes were also related to insulin levels in men (r = 0.23, p <0.05; r = 0.02, p <0.05). In a multiple regression analysis, the association between blood pressure and insulin level was diminished with an allowance for adiposity; however, it remained statistically significant. These data indicate that blood pressure is related to insulin levels in nondiabetic subjects and suggest that insulin may be a physiologic determinant of blood pressure.
UR - http://www.scopus.com/inward/record.url?scp=0022497351&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022497351&partnerID=8YFLogxK
U2 - 10.1016/0002-9343(86)90629-7
DO - 10.1016/0002-9343(86)90629-7
M3 - Article
C2 - 3518437
AN - SCOPUS:0022497351
VL - 80
SP - 861
EP - 864
JO - American Journal of Medicine
JF - American Journal of Medicine
SN - 0002-9343
IS - 5
ER -