Blood pressure in infant twins

Birth to 6 months of age

Robert S. Levine, Charles H. Hennekens, Robert C. Duncan, Euan G. Robertson, Janet E. Gourley, Janet C. Cassady, Henry Gelband

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

To describe the time course of the early development of genetic variance for blood pressure, a cohort of twins is being followed from birth to 1 year of age. The present interim report describes systolic and diastolic blood pressure measurements for 102 twin pairs (39 monozygotic (MZ) and 63 dizygotic (DZ) in the newborn period and at 1, 3 and 6 months of age. Mean values for both systolic and diastolic blood pressure were similar regardless of race, sex, zygosity, or chorionlcity. Statistically significant genetic variance was detected for systolic blood pressure at 6 months of age but not for diastolic blood pressure at any data point. The data are consistent with the hypothesis that genetic factors that determine within-family similarities of blood pressure may be detected early in life, and support the need for further investigation of both genetic and environmental determinants of blood pressure in young populations.

Original languageEnglish (US)
Pages (from-to)I-29-I-33
JournalHypertension
Volume2
Issue number4
StatePublished - 1980
Externally publishedYes

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Parturition
Blood Pressure
Newborn Infant
Population

Keywords

  • Blood pressure
  • Genetic variance
  • Infancy

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Levine, R. S., Hennekens, C. H., Duncan, R. C., Robertson, E. G., Gourley, J. E., Cassady, J. C., & Gelband, H. (1980). Blood pressure in infant twins: Birth to 6 months of age. Hypertension, 2(4), I-29-I-33.

Blood pressure in infant twins : Birth to 6 months of age. / Levine, Robert S.; Hennekens, Charles H.; Duncan, Robert C.; Robertson, Euan G.; Gourley, Janet E.; Cassady, Janet C.; Gelband, Henry.

In: Hypertension, Vol. 2, No. 4, 1980, p. I-29-I-33.

Research output: Contribution to journalArticle

Levine, RS, Hennekens, CH, Duncan, RC, Robertson, EG, Gourley, JE, Cassady, JC & Gelband, H 1980, 'Blood pressure in infant twins: Birth to 6 months of age', Hypertension, vol. 2, no. 4, pp. I-29-I-33.
Levine RS, Hennekens CH, Duncan RC, Robertson EG, Gourley JE, Cassady JC et al. Blood pressure in infant twins: Birth to 6 months of age. Hypertension. 1980;2(4):I-29-I-33.
Levine, Robert S. ; Hennekens, Charles H. ; Duncan, Robert C. ; Robertson, Euan G. ; Gourley, Janet E. ; Cassady, Janet C. ; Gelband, Henry. / Blood pressure in infant twins : Birth to 6 months of age. In: Hypertension. 1980 ; Vol. 2, No. 4. pp. I-29-I-33.
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