Blood Pressure, Depression, and Suicidal Ideation Among Pregnant Women with HIV

Lissa N. Mandell, Manasi S. Parrish, Violeta J. Rodriguez, Maria L. Alcaide, Stephen M. Weiss, Karl Peltzer, Deborah L. Jones

Research output: Contribution to journalArticlepeer-review


Although prior research has examined associations between blood pressure (BP), depression, and suicidal ideation, few studies have examined this in high-risk populations such as pregnant women with HIV (WHIV). The current study examined the association of BP with depression and suicidal ideation among pregnant WHIV (n = 217) in rural South Africa. BP data (measured ≤ 1 month before the study visit) was extracted from medical records. Depressive symptomatology and suicidal ideation were assessed using the Edinburgh Postnatal Depression Scale. Diastolic BP was positively associated with both suicidal ideation and depressive symptomatology, even after controlling for demographic variables, gestational age, and intimate partner violence. These findings suggest that WHIV with elevated BP may be at greater risk for antenatal depression and suicidal ideation. Future research should utilize longitudinal designs to examine potential mechanisms and the directionality of the relationship, as well as other contributing factors.

Original languageEnglish (US)
JournalAIDS and Behavior
StateAccepted/In press - 2021
Externally publishedYes


  • Blood pressure
  • Depression
  • HIV
  • Pregnancy
  • Suicidal ideation

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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