Bleb-related ocular infection in children after trabeculectomy with mitomycin C

S. Waheed, D. C. Ritterband, David Greenfield, J. M. Liebmann, P. A. Sidoti, R. Ritch

Research output: Contribution to journalArticle

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Abstract

Objective: The purpose of the study is to report the clinical course of bleb-related ocular infection in children after trabeculectomy with adjunctive mitomycin C. Design: The study design was a retrospective review of all patients with a diagnosis of bleb-related ocular infection after trabeculectomy with adjunctive mitomycin C. Participants: Three children were identified in whom late postoperative bleb-related ocular infection developed. Intervention: Treatment consisted of vitreous biopsy with intravitreous antibiotic and corticosteroid injection and/or bleb culture with topical and intravenous antibiotic administration. Main Outcome Measures: Visual acuity and intraocular pressure were measured. Results: Bleb-related ocular infection developed an average of 16.7 ± 10.9 months after trabeculectomy (range, 4-23 months). The mean age at presentation was 7.0 ± 2.6 years (range, 4-10 years). Vitreous cultures were positive for staphylococci in two cases. A bleb culture from the third case also grew staphylococcus. All of the children recovered their initial vision after treatment of infection. However, one lost six lines of vision after a subsequent retinal detachment. Additional glaucoma surgery was required in one patient. Conclusions: Late bleb-related ocular infection may occur in children after trabeculectomy with mitomycin C and is characterized by abrupt onset, bleb infiltration, and rapid progression. Despite early preservation of vision after treatment of infection, significant late visual loss can occur.

Original languageEnglish
Pages (from-to)2117-2120
Number of pages4
JournalOphthalmology
Volume104
Issue number12
StatePublished - Dec 1 1997
Externally publishedYes

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Eye Infections
Trabeculectomy
Mitomycin
Blister
Staphylococcus
Anti-Bacterial Agents
Retinal Detachment
Infection
Intraocular Pressure
Intravenous Administration
Glaucoma
Visual Acuity
Adrenal Cortex Hormones
Therapeutics
Outcome Assessment (Health Care)
Biopsy
Injections

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Waheed, S., Ritterband, D. C., Greenfield, D., Liebmann, J. M., Sidoti, P. A., & Ritch, R. (1997). Bleb-related ocular infection in children after trabeculectomy with mitomycin C. Ophthalmology, 104(12), 2117-2120.

Bleb-related ocular infection in children after trabeculectomy with mitomycin C. / Waheed, S.; Ritterband, D. C.; Greenfield, David; Liebmann, J. M.; Sidoti, P. A.; Ritch, R.

In: Ophthalmology, Vol. 104, No. 12, 01.12.1997, p. 2117-2120.

Research output: Contribution to journalArticle

Waheed, S, Ritterband, DC, Greenfield, D, Liebmann, JM, Sidoti, PA & Ritch, R 1997, 'Bleb-related ocular infection in children after trabeculectomy with mitomycin C', Ophthalmology, vol. 104, no. 12, pp. 2117-2120.
Waheed S, Ritterband DC, Greenfield D, Liebmann JM, Sidoti PA, Ritch R. Bleb-related ocular infection in children after trabeculectomy with mitomycin C. Ophthalmology. 1997 Dec 1;104(12):2117-2120.
Waheed, S. ; Ritterband, D. C. ; Greenfield, David ; Liebmann, J. M. ; Sidoti, P. A. ; Ritch, R. / Bleb-related ocular infection in children after trabeculectomy with mitomycin C. In: Ophthalmology. 1997 ; Vol. 104, No. 12. pp. 2117-2120.
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