Abstract
The development of “replacement parts” for humans has been the dream of clinicians ever since solitary organ dysfunction has been identified as the cause of morbidity and mortality in otherwise healthy humans. Organ transplantation has been used successfully to prolong and improve life for countless patients but has also introduced new disease processes and morbidities that force us to look for better solutions. Autologous tissue and organ transplantation is seen as the ultimate goal, as the ability to grow replacement organs and tissues would revolutionize the care of patients with organ failure and does not come burdened with the risk of immunologic rejection. In this summary, we will describe the history and techniques of tissue and organ engineering and its promise to provide autologous bladder tissue for use in children with bladder disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 241-244 |
| Number of pages | 4 |
| Journal | Current Bladder Dysfunction Reports |
| Volume | 10 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 1 2015 |
| Externally published | Yes |
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Keywords
- Autologous
- Bladder
- Neurogenic bladder
- Stem cells
- Tissue engineering
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
Cite this
Bladder Tissue Engineering for Pediatric Urology. / Hodges, Steve J.; Atala, Anthony.
In: Current Bladder Dysfunction Reports, Vol. 10, No. 3, 01.09.2015, p. 241-244.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Bladder Tissue Engineering for Pediatric Urology
AU - Hodges, Steve J.
AU - Atala, Anthony
PY - 2015/9/1
Y1 - 2015/9/1
N2 - The development of “replacement parts” for humans has been the dream of clinicians ever since solitary organ dysfunction has been identified as the cause of morbidity and mortality in otherwise healthy humans. Organ transplantation has been used successfully to prolong and improve life for countless patients but has also introduced new disease processes and morbidities that force us to look for better solutions. Autologous tissue and organ transplantation is seen as the ultimate goal, as the ability to grow replacement organs and tissues would revolutionize the care of patients with organ failure and does not come burdened with the risk of immunologic rejection. In this summary, we will describe the history and techniques of tissue and organ engineering and its promise to provide autologous bladder tissue for use in children with bladder disease.
AB - The development of “replacement parts” for humans has been the dream of clinicians ever since solitary organ dysfunction has been identified as the cause of morbidity and mortality in otherwise healthy humans. Organ transplantation has been used successfully to prolong and improve life for countless patients but has also introduced new disease processes and morbidities that force us to look for better solutions. Autologous tissue and organ transplantation is seen as the ultimate goal, as the ability to grow replacement organs and tissues would revolutionize the care of patients with organ failure and does not come burdened with the risk of immunologic rejection. In this summary, we will describe the history and techniques of tissue and organ engineering and its promise to provide autologous bladder tissue for use in children with bladder disease.
KW - Autologous
KW - Bladder
KW - Neurogenic bladder
KW - Stem cells
KW - Tissue engineering
UR - http://www.scopus.com/inward/record.url?scp=84941641167&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84941641167&partnerID=8YFLogxK
U2 - 10.1007/s11884-015-0318-3
DO - 10.1007/s11884-015-0318-3
M3 - Article
AN - SCOPUS:84941641167
VL - 10
SP - 241
EP - 244
JO - Current Bladder Dysfunction Reports
JF - Current Bladder Dysfunction Reports
SN - 1931-7212
IS - 3
ER -