Black and white patients response to antidepressant treatment for major depression

Roy V. Varner, Pedro Ruiz, David R. Small

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Differences in response to psychopharmacologic agents according to race has so far primarily focused on investigations related to the response of Asian-American patients to neuroleptics and lithium. In this article, we present evidence which depicts that black patients need lower doses of tricyclic antidepressants (TCAs) than white patients to attain a similar response in the treatment of major depression. Likewise, we also advance that black patients might need lower doses of selective serotonin re-uptake inhibitor antidepressants (SSRIs) than white patients to attain a similar response in the treatment of major depression. Further studies are suggested to confirm these findings.

Original languageEnglish
Pages (from-to)117-125
Number of pages9
JournalPsychiatric Quarterly
Volume69
Issue number2
DOIs
StatePublished - Jun 10 1998
Externally publishedYes

Fingerprint

Antidepressive Agents
Therapeutics
Asian Americans
Tricyclic Antidepressive Agents
Serotonin Uptake Inhibitors
Lithium
Antipsychotic Agents
hydroquinone

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Black and white patients response to antidepressant treatment for major depression. / Varner, Roy V.; Ruiz, Pedro; Small, David R.

In: Psychiatric Quarterly, Vol. 69, No. 2, 10.06.1998, p. 117-125.

Research output: Contribution to journalArticle

Varner, Roy V. ; Ruiz, Pedro ; Small, David R. / Black and white patients response to antidepressant treatment for major depression. In: Psychiatric Quarterly. 1998 ; Vol. 69, No. 2. pp. 117-125.
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