Bispectral Index® and the incidence of apnea during monitored anesthesia care

Roy G. Soto, Eugene S. Fu, Robert A. Smith, Rafael V. Miguel

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Purpose: The Bispectral Index (BIS) provides an estimate of depth of consciousness during sedation. If apnea can be shown to correlate with BIS, then a potential improvement in safety during MAC/sedation may be achieved. Scope: Ninety-nine patients undergoing MAC anesthesia were monitored with BIS for level of consciousness, and capnography for apnea detection. The anesthesia provider was blinded to BIS and capnography data. Forty-nine percent of subjects experienced apnea independent of medical history, procedure, or medication. BIS immediately preceding apneic episodes (55 ± 18) was frequently lower than that recommended for an upper limit during general anesthetics (<60). The incidence increased as depth of consciousness decreased with a 50% likelihood of developing apnea at a BIS of 56. Conclusions: The incidence of apnea during MAC is high, and incidence increases as BIS decreases.

Original languageEnglish (US)
Pages (from-to)81-84
Number of pages4
JournalAmbulatory Surgery
Issue number2
StatePublished - Nov 2005


  • Apnea
  • Depth of consciousness
  • Monitored anesthesia care

ASJC Scopus subject areas

  • Medicine(all)
  • Surgery


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