Bipolar affective disorders linked to DNA markers on chromosome 11

Janice A. Egeland, Daniela S. Gerhard, David L. Pauls, James N. Sussex, Kenneth K. Kidd, Cleona R. Alien, Abram M. Hostetter, David E. Housman

Research output: Contribution to journalArticlepeer-review

552 Scopus citations

Abstract

An analysis of the segregation of restriction fragment length polymorphisms in an Old Order Amish pedigree has made it possible to localize a dominant gene conferring a strong predisposition to manic depressive disease to the tip of the short arm of chromosome 11.

Original languageEnglish (US)
Pages (from-to)783-787
Number of pages5
JournalNature
Volume325
Issue number6107
DOIs
StatePublished - Jan 1 1987

ASJC Scopus subject areas

  • General

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