Bioprinting technology and its applications

Young Joon Seol, Hyun Wook Kang, Sang Jin Lee, Anthony Atala, James J. Yoo

Research output: Contribution to journalReview article

137 Scopus citations

Abstract

Bioprinting technology has emerged as a powerful tool for building tissue and organ structures in the field of tissue engineering. This technology allows precise placement of cells, biomaterials and biomolecules in spatially predefined locations within confined three-dimensional (3D) structures. Various bioprinting technologies have been developed and utilized for applications in life sciences, ranging from studying cellular mechanisms to constructing tissues and organs for implantation, including heart valve, myocardial tissue, trachea and blood vessels. In this article, we introduce the general principles and limitations of the most widely used bioprinting technologies, including jetting- and extrusion-based systems. Application-based research focused on tissue regeneration is presented, as well as the current challenges that hamper clinical utility of bioprinting technology.

Original languageEnglish (US)
Article numberezu148
Pages (from-to)342-348
Number of pages7
JournalEuropean Journal of Cardio-Thoracic Surgery
Volume46
Issue number3
DOIs
StatePublished - Sep 2014

Keywords

  • Bioprinting
  • Reconstruction
  • Regenerative medicine

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine

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  • Cite this

    Seol, Y. J., Kang, H. W., Lee, S. J., Atala, A., & Yoo, J. J. (2014). Bioprinting technology and its applications. European Journal of Cardio-Thoracic Surgery, 46(3), 342-348. [ezu148]. https://doi.org/10.1093/ejcts/ezu148