Bioprinted scaffolds for cartilage tissue engineering

Hyun Wook Kang, James J. Yoo, Anthony Atala

Research output: Chapter in Book/Report/Conference proceedingChapter

14 Scopus citations

Abstract

Researchers are focusing on bioprinting technology as a viable option to overcome current difficulties in cartilage tissue engineering. Bioprinting enables a three-dimensional (3-D), free-form, computer-designed structure using biomaterials, biomolecules, and/or cells. The inner and outer shape of a scaffold can be controlled by this technology with great precision. Here, we introduce a hybrid bioprinting technology that is a co-printing process of multiple materials including high-strength synthetic polymer and cell-laden hydrogel. The synthetic polymer provides mechanical support for shape maintenance and load bearing, while the hydrogel provides the biological environment for artificial cartilage regeneration. This chapter introduces the procedures for printing of a 3-D scaffold using our hybrid bioprinting technology and includes the source materials for preparation of 3-D printing

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages161-169
Number of pages9
Volume1340
DOIs
StatePublished - 2015

Publication series

NameMethods in Molecular Biology
Volume1340
ISSN (Print)10643745

Keywords

  • Bioprinting
  • Cartilage
  • Cell printing
  • Chondrocyte
  • Fibrin gel
  • Polycaprolactone
  • Scaffold

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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  • Cite this

    Kang, H. W., Yoo, J. J., & Atala, A. (2015). Bioprinted scaffolds for cartilage tissue engineering. In Methods in Molecular Biology (Vol. 1340, pp. 161-169). (Methods in Molecular Biology; Vol. 1340). Humana Press Inc.. https://doi.org/10.1007/978-1-4939-2938-2_11