Abstract
The acute phase response (APR) is a key part of the innate immune system and acute phase proteins (APPs) represent the core of the early response to stimuli such as trauma, infection, stress, neoplasia, and autoimmune disease. These biomarkers have a different timeline and magnitude of expression vs traditional means of examining inflammation (e.g., total white blood count and albumin/globulin (A/G) ratio). Extensive studies conducted in companion and large animals have demonstrated many clinical applications for inflammatory biomarkers including diagnosis, prognosis, detection of subclinical disease and chronic inflammation, and monitoring stress. This article provides information regarding the APR and the uses of APP quantitation, as well as the growing body of information on APPSs in exotic animals.
| Original language | English |
|---|---|
| Pages (from-to) | 245-250 |
| Number of pages | 6 |
| Journal | Journal of Exotic Pet Medicine |
| Volume | 22 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jul 1 2013 |
Fingerprint
Keywords
- Acute phase protein
- Acute phase response
- Biomarker
- Haptoglobin
- Inflammation
- Serum amyloid A
ASJC Scopus subject areas
- veterinary(all)
Cite this
Biomarkers of Inflammation in Exotic Pets. / Cray, Carolyn.
In: Journal of Exotic Pet Medicine, Vol. 22, No. 3, 01.07.2013, p. 245-250.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Biomarkers of Inflammation in Exotic Pets
AU - Cray, Carolyn
PY - 2013/7/1
Y1 - 2013/7/1
N2 - The acute phase response (APR) is a key part of the innate immune system and acute phase proteins (APPs) represent the core of the early response to stimuli such as trauma, infection, stress, neoplasia, and autoimmune disease. These biomarkers have a different timeline and magnitude of expression vs traditional means of examining inflammation (e.g., total white blood count and albumin/globulin (A/G) ratio). Extensive studies conducted in companion and large animals have demonstrated many clinical applications for inflammatory biomarkers including diagnosis, prognosis, detection of subclinical disease and chronic inflammation, and monitoring stress. This article provides information regarding the APR and the uses of APP quantitation, as well as the growing body of information on APPSs in exotic animals.
AB - The acute phase response (APR) is a key part of the innate immune system and acute phase proteins (APPs) represent the core of the early response to stimuli such as trauma, infection, stress, neoplasia, and autoimmune disease. These biomarkers have a different timeline and magnitude of expression vs traditional means of examining inflammation (e.g., total white blood count and albumin/globulin (A/G) ratio). Extensive studies conducted in companion and large animals have demonstrated many clinical applications for inflammatory biomarkers including diagnosis, prognosis, detection of subclinical disease and chronic inflammation, and monitoring stress. This article provides information regarding the APR and the uses of APP quantitation, as well as the growing body of information on APPSs in exotic animals.
KW - Acute phase protein
KW - Acute phase response
KW - Biomarker
KW - Haptoglobin
KW - Inflammation
KW - Serum amyloid A
UR - http://www.scopus.com/inward/record.url?scp=84887082366&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84887082366&partnerID=8YFLogxK
U2 - 10.1053/j.jepm.2013.08.003
DO - 10.1053/j.jepm.2013.08.003
M3 - Article
AN - SCOPUS:84887082366
VL - 22
SP - 245
EP - 250
JO - Journal of Exotic Pet Medicine
JF - Journal of Exotic Pet Medicine
SN - 1557-5063
IS - 3
ER -