Biomarkers of Inflammation in Exotic Pets

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The acute phase response (APR) is a key part of the innate immune system and acute phase proteins (APPs) represent the core of the early response to stimuli such as trauma, infection, stress, neoplasia, and autoimmune disease. These biomarkers have a different timeline and magnitude of expression vs traditional means of examining inflammation (e.g., total white blood count and albumin/globulin (A/G) ratio). Extensive studies conducted in companion and large animals have demonstrated many clinical applications for inflammatory biomarkers including diagnosis, prognosis, detection of subclinical disease and chronic inflammation, and monitoring stress. This article provides information regarding the APR and the uses of APP quantitation, as well as the growing body of information on APPSs in exotic animals.

Original languageEnglish
Pages (from-to)245-250
Number of pages6
JournalJournal of Exotic Pet Medicine
Volume22
Issue number3
DOIs
StatePublished - Jul 1 2013

Fingerprint

Acute-Phase Reaction
acute phase proteins
Acute-Phase Proteins
pets
biomarkers
inflammation
Biomarkers
Inflammation
disease detection
autoimmune diseases
Pets
Globulins
globulins
Autoimmune Diseases
prognosis
albumins
Albumins
Immune System
animals
Chronic Disease

Keywords

  • Acute phase protein
  • Acute phase response
  • Biomarker
  • Haptoglobin
  • Inflammation
  • Serum amyloid A

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Biomarkers of Inflammation in Exotic Pets. / Cray, Carolyn.

In: Journal of Exotic Pet Medicine, Vol. 22, No. 3, 01.07.2013, p. 245-250.

Research output: Contribution to journalArticle

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