Biomarker profiling for cancer diagnosis, prognosis and therapeutic management

Anirban P. Mitra, Henry Lin, Richard J. Cote, Ram H. Datar

Research output: Contribution to journalReview article

20 Scopus citations

Abstract

The basis of cancer treatment has come a long way since the days of the the classical TNM staging. Identification of novel biomarkers for various cancers and their specific correlations with prognosis have increased our understanding of carcinogenesis and tumour progression on the molecular level. Recent advances in technologies for simultaneous detection of multiple biomarkers have opened up new avenues for multimarker proflilng on a more individual scale. We summarize the key molecular determinants and their prognostic role in various cancers, and examine the available techniques for analysing biomarker panels that can have a major impact on cancer diagnostics and therapeutics.

Original languageEnglish (US)
Pages (from-to)304-312
Number of pages9
JournalNational Medical Journal of India
Volume18
Issue number6
StatePublished - Nov 1 2005

ASJC Scopus subject areas

  • Medicine(all)

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