Biocompatible microcapsules for in-vivo transplantation of animal tissue

Amarpreet S. Sawhney, Patrick Soon-Shiong, Jeffrey A. Hubbell

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Microcapsules made out of ionically crosslinked membranes of alginate and Poly(l-lysine) (PLL) have been extensively used for the encapsulation of animal tissue in immunoprotective membrane microspheres. However, biocompativility remain a stumbling block in the long term survival of these grafts. Membranes with enhanced biocompatiblity have been made by using a novel graft copolymer of PLL and poly(ethylene oxide) (PEO) instead of the PLL homopolymer.

Original languageEnglish
Title of host publicationTransactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
Place of PublicationAlgonquin, IL, United States
PublisherPubl by Soc for Biomaterials
Volume14
StatePublished - Jan 1 1991
Externally publishedYes
Event17th Annual Meeting of the Society for Biomaterials in conjunction with the 23rd International Biomaterials Symposium - Scottsdale, AZ, USA
Duration: May 1 1991May 5 1991

Other

Other17th Annual Meeting of the Society for Biomaterials in conjunction with the 23rd International Biomaterials Symposium
CityScottsdale, AZ, USA
Period5/1/915/5/91

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ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Sawhney, A. S., Soon-Shiong, P., & Hubbell, J. A. (1991). Biocompatible microcapsules for in-vivo transplantation of animal tissue. In Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium (Vol. 14). Publ by Soc for Biomaterials.