Biocompatible dispersions of carbon nanotubes: A potential tool for intracellular transport of anticancer drugs

Antonello Di Crescenzo; Diana Velluto; Jeffrey A. Hubbell; Antonella Fontana

doi:10.1039/c0nr00444h

Biocompatible dispersions of carbon nanotubes: A potential tool for intracellular transport of anticancer drugs

Antonello Di Crescenzo, Diana Velluto, Jeffrey A. Hubbell, Antonella Fontana

Surgery

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

The use of the biocompatible amphiphilic diblock copolymer poly(ethylene glycol-b-propylene sulfide) (PEG₄₄PPS₂₀) allows a tuned loading of doxorubicin onto the surface of non-functionalized multi-walled carbon nanotubes and an efficient cell internalization. The obtained multi-walled carbon nanotube-based systems show enhanced cytotoxic activity with respect to non-vehicled doxorubicin.

Original language	English (US)
Pages (from-to)	925-928
Number of pages	4
Journal	Nanoscale
Volume	3
Issue number	3
DOIs	https://doi.org/10.1039/c0nr00444h
State	Published - Mar 1 2011

ASJC Scopus subject areas

Materials Science(all)

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10.1039/c0nr00444h

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abstract = "The use of the biocompatible amphiphilic diblock copolymer poly(ethylene glycol-b-propylene sulfide) (PEG44PPS20) allows a tuned loading of doxorubicin onto the surface of non-functionalized multi-walled carbon nanotubes and an efficient cell internalization. The obtained multi-walled carbon nanotube-based systems show enhanced cytotoxic activity with respect to non-vehicled doxorubicin.",

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