Biocompatible dispersions of carbon nanotubes: A potential tool for intracellular transport of anticancer drugs

Antonello Di Crescenzo; Diana Velluto; Jeffrey A. Hubbell; Antonella Fontana

doi:10.1039/c0nr00444h

Biocompatible dispersions of carbon nanotubes: A potential tool for intracellular transport of anticancer drugs

Antonello Di Crescenzo, Diana Velluto, Jeffrey A. Hubbell, Antonella Fontana

Surgery

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

The use of the biocompatible amphiphilic diblock copolymer poly(ethylene glycol-b-propylene sulfide) (PEG₄₄PPS₂₀) allows a tuned loading of doxorubicin onto the surface of non-functionalized multi-walled carbon nanotubes and an efficient cell internalization. The obtained multi-walled carbon nanotube-based systems show enhanced cytotoxic activity with respect to non-vehicled doxorubicin.

Original language	English (US)
Pages (from-to)	925-928
Number of pages	4
Journal	Nanoscale
Volume	3
Issue number	3
DOIs	https://doi.org/10.1039/c0nr00444h
State	Published - Mar 1 2011

ASJC Scopus subject areas

Materials Science(all)

Access to Document

10.1039/c0nr00444h

Cite this

@article{ba46250129174bae9d4f4d602aab5b0e,

title = "Biocompatible dispersions of carbon nanotubes: A potential tool for intracellular transport of anticancer drugs",

abstract = "The use of the biocompatible amphiphilic diblock copolymer poly(ethylene glycol-b-propylene sulfide) (PEG44PPS20) allows a tuned loading of doxorubicin onto the surface of non-functionalized multi-walled carbon nanotubes and an efficient cell internalization. The obtained multi-walled carbon nanotube-based systems show enhanced cytotoxic activity with respect to non-vehicled doxorubicin.",

author = "{Di Crescenzo}, Antonello and Diana Velluto and Hubbell, {Jeffrey A.} and Antonella Fontana",

year = "2011",

month = mar,

day = "1",

doi = "10.1039/c0nr00444h",

language = "English (US)",

volume = "3",

pages = "925--928",

journal = "Nanoscale",

issn = "2040-3364",

publisher = "Royal Society of Chemistry",

number = "3",

}

TY - JOUR

T1 - Biocompatible dispersions of carbon nanotubes

T2 - A potential tool for intracellular transport of anticancer drugs

AU - Di Crescenzo, Antonello

AU - Velluto, Diana

AU - Hubbell, Jeffrey A.

AU - Fontana, Antonella

PY - 2011/3/1

Y1 - 2011/3/1

N2 - The use of the biocompatible amphiphilic diblock copolymer poly(ethylene glycol-b-propylene sulfide) (PEG44PPS20) allows a tuned loading of doxorubicin onto the surface of non-functionalized multi-walled carbon nanotubes and an efficient cell internalization. The obtained multi-walled carbon nanotube-based systems show enhanced cytotoxic activity with respect to non-vehicled doxorubicin.

AB - The use of the biocompatible amphiphilic diblock copolymer poly(ethylene glycol-b-propylene sulfide) (PEG44PPS20) allows a tuned loading of doxorubicin onto the surface of non-functionalized multi-walled carbon nanotubes and an efficient cell internalization. The obtained multi-walled carbon nanotube-based systems show enhanced cytotoxic activity with respect to non-vehicled doxorubicin.

UR - http://www.scopus.com/inward/record.url?scp=79952665482&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79952665482&partnerID=8YFLogxK

U2 - 10.1039/c0nr00444h

DO - 10.1039/c0nr00444h

M3 - Article

C2 - 21180768

AN - SCOPUS:79952665482

VL - 3

SP - 925

EP - 928

JO - Nanoscale

JF - Nanoscale

SN - 2040-3364

IS - 3

ER -

Biocompatible dispersions of carbon nanotubes: A potential tool for intracellular transport of anticancer drugs

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this