Abstract
Engineering principles are used in the exploitation of biocatalysts derived from cells. The purity of reagents, catalysts and maintenance of operation variables are extremely important for bioengineering systems. Any change in the purity of reagents or in operation variables usually leads to a dramatic decrease in productivity. Cellular systems, however, are able to work with relatively high impure conditions and increase their productivity in response to external signals. Thus the seemingly disordered 'bag of juice' or cytoplasm has more order and much higher order of integration than first appears. Learning the semantics of this paradoxical ability of order and integration would help bioengineers to understand and enhance productivity even using impure reagents.
| Original language | English |
|---|---|
| Pages (from-to) | 204-209 |
| Number of pages | 6 |
| Journal | Trends in Biotechnology |
| Volume | 21 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 1 2003 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Bioengineering
Cite this
Biochemical engineering : Cues from cells. / Chakrabarti, Subhra; Bhattacharya, Sumana; Bhattacharya, Sanjoy K.
In: Trends in Biotechnology, Vol. 21, No. 5, 01.05.2003, p. 204-209.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Biochemical engineering
T2 - Cues from cells
AU - Chakrabarti, Subhra
AU - Bhattacharya, Sumana
AU - Bhattacharya, Sanjoy K
PY - 2003/5/1
Y1 - 2003/5/1
N2 - Engineering principles are used in the exploitation of biocatalysts derived from cells. The purity of reagents, catalysts and maintenance of operation variables are extremely important for bioengineering systems. Any change in the purity of reagents or in operation variables usually leads to a dramatic decrease in productivity. Cellular systems, however, are able to work with relatively high impure conditions and increase their productivity in response to external signals. Thus the seemingly disordered 'bag of juice' or cytoplasm has more order and much higher order of integration than first appears. Learning the semantics of this paradoxical ability of order and integration would help bioengineers to understand and enhance productivity even using impure reagents.
AB - Engineering principles are used in the exploitation of biocatalysts derived from cells. The purity of reagents, catalysts and maintenance of operation variables are extremely important for bioengineering systems. Any change in the purity of reagents or in operation variables usually leads to a dramatic decrease in productivity. Cellular systems, however, are able to work with relatively high impure conditions and increase their productivity in response to external signals. Thus the seemingly disordered 'bag of juice' or cytoplasm has more order and much higher order of integration than first appears. Learning the semantics of this paradoxical ability of order and integration would help bioengineers to understand and enhance productivity even using impure reagents.
UR - http://www.scopus.com/inward/record.url?scp=0037406250&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037406250&partnerID=8YFLogxK
U2 - 10.1016/S0167-7799(03)00077-5
DO - 10.1016/S0167-7799(03)00077-5
M3 - Article
C2 - 12727381
AN - SCOPUS:0037406250
VL - 21
SP - 204
EP - 209
JO - Trends in Biotechnology
JF - Trends in Biotechnology
SN - 0167-7799
IS - 5
ER -