Biochemical effects of the plant Lantana camara on guinea pig liver mitochondria

O. P. Sharma, H. P.S. Makkar, Rajinder Dawra

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Lantana camara caused, in guinea pigs, a decrease in hepatic mitochondrial protein content. The phospholipid to protein ratio did not change but there was a marked increase in the cholesterol to protein ratio and the cholesterol to phospholipid ratio. Enzyme activities of succinic dehydrogenase, glutamate dehydrogenase, cytochrome oxidase and Mg2+-ATPase increased, while the activity of NADH-ferricyanide reductase remained unaffected. Mitochondrial swelling, in the absence or presence of ascorbic acid, decreased in hepatic mitochondria from lantana-intoxicated guinea pigs.

Original languageEnglish (US)
Pages (from-to)783-786
Number of pages4
JournalToxicon
Volume20
Issue number4
DOIs
StatePublished - Jan 1 1982
Externally publishedYes

Fingerprint

Lantana
Mitochondria
Liver Mitochondrion
Liver
Phospholipids
Guinea Pigs
Cholesterol
Mitochondrial Swelling
Ca(2+) Mg(2+)-ATPase
Glutamate Dehydrogenase
Succinate Dehydrogenase
Mitochondrial Proteins
Enzyme activity
Electron Transport Complex IV
Ascorbic Acid
Swelling
Proteins
Enzymes

ASJC Scopus subject areas

  • Toxicology

Cite this

Biochemical effects of the plant Lantana camara on guinea pig liver mitochondria. / Sharma, O. P.; Makkar, H. P.S.; Dawra, Rajinder.

In: Toxicon, Vol. 20, No. 4, 01.01.1982, p. 783-786.

Research output: Contribution to journalArticle

Sharma, O. P. ; Makkar, H. P.S. ; Dawra, Rajinder. / Biochemical effects of the plant Lantana camara on guinea pig liver mitochondria. In: Toxicon. 1982 ; Vol. 20, No. 4. pp. 783-786.
@article{17faf3d14dbc431e83434219e16b8002,
title = "Biochemical effects of the plant Lantana camara on guinea pig liver mitochondria",
abstract = "Lantana camara caused, in guinea pigs, a decrease in hepatic mitochondrial protein content. The phospholipid to protein ratio did not change but there was a marked increase in the cholesterol to protein ratio and the cholesterol to phospholipid ratio. Enzyme activities of succinic dehydrogenase, glutamate dehydrogenase, cytochrome oxidase and Mg2+-ATPase increased, while the activity of NADH-ferricyanide reductase remained unaffected. Mitochondrial swelling, in the absence or presence of ascorbic acid, decreased in hepatic mitochondria from lantana-intoxicated guinea pigs.",
author = "Sharma, {O. P.} and Makkar, {H. P.S.} and Rajinder Dawra",
year = "1982",
month = "1",
day = "1",
doi = "10.1016/0041-0101(82)90125-8",
language = "English (US)",
volume = "20",
pages = "783--786",
journal = "Toxicon",
issn = "0041-0101",
publisher = "Elsevier Limited",
number = "4",

}

TY - JOUR

T1 - Biochemical effects of the plant Lantana camara on guinea pig liver mitochondria

AU - Sharma, O. P.

AU - Makkar, H. P.S.

AU - Dawra, Rajinder

PY - 1982/1/1

Y1 - 1982/1/1

N2 - Lantana camara caused, in guinea pigs, a decrease in hepatic mitochondrial protein content. The phospholipid to protein ratio did not change but there was a marked increase in the cholesterol to protein ratio and the cholesterol to phospholipid ratio. Enzyme activities of succinic dehydrogenase, glutamate dehydrogenase, cytochrome oxidase and Mg2+-ATPase increased, while the activity of NADH-ferricyanide reductase remained unaffected. Mitochondrial swelling, in the absence or presence of ascorbic acid, decreased in hepatic mitochondria from lantana-intoxicated guinea pigs.

AB - Lantana camara caused, in guinea pigs, a decrease in hepatic mitochondrial protein content. The phospholipid to protein ratio did not change but there was a marked increase in the cholesterol to protein ratio and the cholesterol to phospholipid ratio. Enzyme activities of succinic dehydrogenase, glutamate dehydrogenase, cytochrome oxidase and Mg2+-ATPase increased, while the activity of NADH-ferricyanide reductase remained unaffected. Mitochondrial swelling, in the absence or presence of ascorbic acid, decreased in hepatic mitochondria from lantana-intoxicated guinea pigs.

UR - http://www.scopus.com/inward/record.url?scp=0020459870&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020459870&partnerID=8YFLogxK

U2 - 10.1016/0041-0101(82)90125-8

DO - 10.1016/0041-0101(82)90125-8

M3 - Article

C2 - 7135417

AN - SCOPUS:0020459870

VL - 20

SP - 783

EP - 786

JO - Toxicon

JF - Toxicon

SN - 0041-0101

IS - 4

ER -