Biobehavioral aspects of cardiovascular disease: progress and prospects.

N. Schneiderman, M. A. Chesney, D. S. Krantz

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


Cardiovascular disorders pose a major health problem for industrialized societies in terms of excess morbidity and mortality. Hypertension (HT) is a major risk factor for coronary heart disease (CHD) and cerebrovascular disease. The impact of psychosocial factors, personality traits, genetic-behavioral interactions, sodium sensitivity, obesity, insulin metabolism, and psychophysiology on HT status is discussed. An understanding of pathophysiologic processes is needed to provide a better basis for risk factor reduction and other aspects of treatment. The study of myocardial ischemia appears to provide an important link between the development of coronary artery disease and the occurrence of CHD. Further studies are needed to assess the clinical significance of stress-induced myocardial ischemia as well as whether mental stress is predictive of future CHD. Associations have been made between behavioral risk factors and CHD, but the exact nature of the relationship remains to be clarified. Hostility has been identified as an important aspect of coronary-prone behavior, but considerable research will have to be completed before a comprehensive understanding of coronary-prone behavior and the manner in which it has an impact on disease can be fully understood.

Original languageEnglish (US)
Pages (from-to)649-676
Number of pages28
JournalHealth psychology : official journal of the Division of Health Psychology, American Psychological Association
Issue number6
StatePublished - 1989

ASJC Scopus subject areas

  • Applied Psychology
  • Psychiatry and Mental health


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