@article{59d6b88152e14b3eb8a02dffa0006065,
title = "BioAssay Research Database (BARD): Chemical biology and probe-development enabled by structured metadata and result types",
abstract = "BARD, the BioAssay Research Database (https://bard.nih.gov/) is a public database and suite of tools developed to provide access to bioassay data produced by the NIH Molecular Libraries Program (MLP). Data from 631 MLP projects were migrated to a new structured vocabulary designed to capture bioassay data in a formalized manner, with particular emphasis placed on the description of assay protocols. New data can be submitted to BARD with a user-friendly set of tools that assist in the creation of appropriately formatted datasets and assay definitions. Data published through the BARD application program interface (API) can be accessed by researchers using web-based query tools or a desktop client. Thirdparty developers wishing to create new tools can use the API to produce stand-alone tools or new plug-ins that can be integrated into BARD. The entire BARD suite of tools therefore supports three classes of researcher: those who wish to publish data, those who wish to mine data for testable hypotheses, and those in the developer community who wish to build tools that leverage this carefully curated chemical biology resource.",
author = "Howe, {E. A.} and {De Souza}, A. and Lahr, {D. L.} and S. Chatwin and P. Montgomery and Alexander, {B. R.} and Nguyen, {D. T.} and Y. Cruz and Stonich, {D. A.} and G. Walzer and Rose, {J. T.} and Picard, {S. C.} and Z. Liu and Rose, {J. N.} and X. Xiang and J. Asiedu and D. Durkin and J. Levine and Yang, {J. J.} and Sch{\"u}rer, {S. C.} and Braisted, {J. C.} and N. Southall and Southern, {M. R.} and Chung, {T. D.Y.} and S. Brudz and C. Tanega and Schreiber, {S. L.} and Bittker, {J. A.} and R. Guha and Clemons, {P. A.}",
note = "Funding Information: National Institutes of Health Common Fund through its Molecular Libraries Probe Production Center Network [RFA-RM-08-005 to BARD] as an administrative supplement directly to the centers following receipt and review of center proposals in response to a request for proposal crafted by Dr. Ajay Pillai (National Human Genome Research Institute). Funding for open access charge: Broad Institute Comprehensive Screening Center (U54-HG005032). Conflict of interest statement. E.A.H., A.D., D.L.L., X.X., J.A., D.D. and J.A.B. are considering a commercial data sciences enterprise that would partner with academic and bio-medical research institutes to commercialize software. This enterprise would use elements of the BARD toolkit and migrated data along with elements of other open source projects.",
year = "2015",
month = jan,
day = "28",
doi = "10.1093/nar/gku1244",
language = "English (US)",
volume = "43",
pages = "D1163--D1170",
journal = "Nucleic Acids Research",
issn = "0305-1048",
publisher = "Oxford University Press",
number = "D1",
}