Bioactive biomaterials for engineering tissue healing

J. A. Hubbell

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The increasingly use of biomimetic approaches in the design for materials for the engineering of tissue healing were discussed. It was found that a particular interest in biomimetic materials was to replace the key features of the extracellular matrix. These include development of materials for cell in-growth matrices in tissue regeneration and wound healing, presentation of adhesion signals and the display of growth factor binding sites. Two important approaches have been employed for tissue healing which include fibrin that represents an interesting platform material as a cell in-growth matrix and the development of synthetic mimicks of fibrin, consisting of water-soluble polymer chains cross-linked by plasmin-sensitive reactive peptides.

Original languageEnglish
Title of host publicationSecond Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling
StatePublished - Dec 1 2000
Externally publishedYes
EventSecond Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling - York, United Kingdom
Duration: Jul 16 2000Jul 19 2000

Other

OtherSecond Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling
CountryUnited Kingdom
CityYork
Period7/16/007/19/00

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ASJC Scopus subject areas

  • Engineering(all)

Cite this

Hubbell, J. A. (2000). Bioactive biomaterials for engineering tissue healing. In Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling