Bio-printing of living organized tissues using an inkjet technology

Tao Xu, Weixin Zhao, Anthony Atala, James J. Yoo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

This study is directed towards developing a novel and versatile method for creating complex tissue structures that use simultaneous ink-jetting of multiple cell types. To demonstrate this concept, 3 different cell types, consisting of human amniotic fluid-derived stem cells (hAFSC), smooth muscle cells (SMC), and bovine aortic endothelial cells (EC), were printed by a thermal inkjet printer to form a heterogeneous cell configuration. Each of the printed cell types maintained viability, proliferation, phenotypic expression, and normal physiological function within the complex structures in-vitro. The bio-printed constructs were able to survive and mature into functional tissues with adequate vascularization in vivo. These findings demonstrate that fabrication of complex hybrid tissue structures that require multiple cell types can be achieved by using the inkjet technology.

Original languageEnglish (US)
Title of host publicationDigital Fabrication 2006 - Final Program and Proceedings
Pages131-134
Number of pages4
StatePublished - Dec 1 2006
EventDigital Fabrication 2006 - Denver, CO, United States
Duration: Sep 17 2006Sep 22 2006

Publication series

NameDigital Fabrication 2006 - Final Program and Proceedings
Volume2006

Other

OtherDigital Fabrication 2006
CountryUnited States
CityDenver, CO
Period9/17/069/22/06

ASJC Scopus subject areas

  • Engineering(all)

Fingerprint Dive into the research topics of 'Bio-printing of living organized tissues using an inkjet technology'. Together they form a unique fingerprint.

  • Cite this

    Xu, T., Zhao, W., Atala, A., & Yoo, J. J. (2006). Bio-printing of living organized tissues using an inkjet technology. In Digital Fabrication 2006 - Final Program and Proceedings (pp. 131-134). (Digital Fabrication 2006 - Final Program and Proceedings; Vol. 2006).