Bio-printing of living organized tissues using an inkjet technology

Tao Xu, Weixin Zhao, Anthony Atala, James J. Yoo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations


This study is directed towards developing a novel and versatile method for creating complex tissue structures that use simultaneous ink-jetting of multiple cell types. To demonstrate this concept, 3 different cell types, consisting of human amniotic fluid-derived stem cells (hAFSC), smooth muscle cells (SMC), and bovine aortic endothelial cells (EC), were printed by a thermal inkjet printer to form a heterogeneous cell configuration. Each of the printed cell types maintained viability, proliferation, phenotypic expression, and normal physiological function within the complex structures in-vitro. The bio-printed constructs were able to survive and mature into functional tissues with adequate vascularization in vivo. These findings demonstrate that fabrication of complex hybrid tissue structures that require multiple cell types can be achieved by using the inkjet technology.

Original languageEnglish (US)
Title of host publicationDigital Fabrication 2006 - Final Program and Proceedings
Number of pages4
StatePublished - 2006
EventDigital Fabrication 2006 - Denver, CO, United States
Duration: Sep 17 2006Sep 22 2006

Publication series

NameDigital Fabrication 2006 - Final Program and Proceedings


OtherDigital Fabrication 2006
Country/TerritoryUnited States
CityDenver, CO

ASJC Scopus subject areas

  • Engineering(all)


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