Abstract
This study is directed towards developing a novel and versatile method for creating complex tissue structures that use simultaneous ink-jetting of multiple cell types. To demonstrate this concept, 3 different cell types, consisting of human amniotic fluid-derived stem cells (hAFSC), smooth muscle cells (SMC), and bovine aortic endothelial cells (EC), were printed by a thermal inkjet printer to form a heterogeneous cell configuration. Each of the printed cell types maintained viability, proliferation, phenotypic expression, and normal physiological function within the complex structures in-vitro. The bio-printed constructs were able to survive and mature into functional tissues with adequate vascularization in vivo. These findings demonstrate that fabrication of complex hybrid tissue structures that require multiple cell types can be achieved by using the inkjet technology.
| Original language | English |
|---|---|
| Title of host publication | Digital Fabrication 2006 - Final Program and Proceedings |
| Pages | 131-134 |
| Number of pages | 4 |
| Volume | 2006 |
| State | Published - Dec 1 2006 |
| Externally published | Yes |
| Event | Digital Fabrication 2006 - Denver, CO, United States Duration: Sep 17 2006 → Sep 22 2006 |
Other
| Other | Digital Fabrication 2006 |
|---|---|
| Country | United States |
| City | Denver, CO |
| Period | 9/17/06 → 9/22/06 |
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ASJC Scopus subject areas
- Engineering(all)
Cite this
Bio-printing of living organized tissues using an inkjet technology. / Xu, Tao; Zhao, Weixin; Atala, Anthony; Yoo, James J.
Digital Fabrication 2006 - Final Program and Proceedings. Vol. 2006 2006. p. 131-134.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Bio-printing of living organized tissues using an inkjet technology
AU - Xu, Tao
AU - Zhao, Weixin
AU - Atala, Anthony
AU - Yoo, James J.
PY - 2006/12/1
Y1 - 2006/12/1
N2 - This study is directed towards developing a novel and versatile method for creating complex tissue structures that use simultaneous ink-jetting of multiple cell types. To demonstrate this concept, 3 different cell types, consisting of human amniotic fluid-derived stem cells (hAFSC), smooth muscle cells (SMC), and bovine aortic endothelial cells (EC), were printed by a thermal inkjet printer to form a heterogeneous cell configuration. Each of the printed cell types maintained viability, proliferation, phenotypic expression, and normal physiological function within the complex structures in-vitro. The bio-printed constructs were able to survive and mature into functional tissues with adequate vascularization in vivo. These findings demonstrate that fabrication of complex hybrid tissue structures that require multiple cell types can be achieved by using the inkjet technology.
AB - This study is directed towards developing a novel and versatile method for creating complex tissue structures that use simultaneous ink-jetting of multiple cell types. To demonstrate this concept, 3 different cell types, consisting of human amniotic fluid-derived stem cells (hAFSC), smooth muscle cells (SMC), and bovine aortic endothelial cells (EC), were printed by a thermal inkjet printer to form a heterogeneous cell configuration. Each of the printed cell types maintained viability, proliferation, phenotypic expression, and normal physiological function within the complex structures in-vitro. The bio-printed constructs were able to survive and mature into functional tissues with adequate vascularization in vivo. These findings demonstrate that fabrication of complex hybrid tissue structures that require multiple cell types can be achieved by using the inkjet technology.
UR - http://www.scopus.com/inward/record.url?scp=33947252840&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33947252840&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:33947252840
SN - 089208264X
SN - 9780892082643
VL - 2006
SP - 131
EP - 134
BT - Digital Fabrication 2006 - Final Program and Proceedings
ER -