Abstract
The biliary excretion of moxalactam was studied in 11 postsurgery patients who had indwelling T-tubes inserted in their common bile ducts. Peak levels of moxalactam in the bile reached mean levels of 33.7 ± 11.1 and 173.7 ± 67.0 μg/ml 2 h after intravenous administration of a single 500- or 2,000-mg dose, respectively. In 5 of the 10 patients given the 2,000-mg dose, peak moxalactam concentrations in the bile were 2 to 12 times higher than simultaneous serum levels, but considerable variation in the biliary excretion of maxalactam was observed among the individual patients.
Original language | English (US) |
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Pages (from-to) | 231-234 |
Number of pages | 4 |
Journal | Unknown Journal |
Volume | 20 |
Issue number | 2 |
DOIs | |
State | Published - 1981 |
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
- Infectious Diseases