Biliary excretion of moxalactam

O. V. Martinez, J. U. Levi, A. Livingstone, T. I. Malinin, R. Zeppa, D. Hutson, N. Einhorn

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The biliary excretion of moxalactam was studied in 11 postsurgery patients who had indwelling T-tubes inserted in their common bile ducts. Peak levels of moxalactam in the bile reached mean levels of 33.7 ± 11.1 and 173.7 ± 67.0 μg/ml 2 h after intravenous administration of a single 500- or 2,000-mg dose, respectively. In 5 of the 10 patients given the 2,000-mg dose, peak moxalactam concentrations in the bile were 2 to 12 times higher than simultaneous serum levels, but considerable variation in the biliary excretion of maxalactam was observed among the individual patients.

Original languageEnglish (US)
Pages (from-to)231-234
Number of pages4
JournalUnknown Journal
Volume20
Issue number2
DOIs
StatePublished - 1981

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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