Biliary excretion of moxalactam

O. V. Martinez; J. U. Levi; A. Livingstone; T. I. Malinin; R. Zeppa; D. Hutson; N. Einhorn

doi:10.1128/AAC.20.2.231

Biliary excretion of moxalactam

O. V. Martinez, J. U. Levi, A. Livingstone, T. I. Malinin, R. Zeppa, D. Hutson, N. Einhorn

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The biliary excretion of moxalactam was studied in 11 postsurgery patients who had indwelling T-tubes inserted in their common bile ducts. Peak levels of moxalactam in the bile reached mean levels of 33.7 ± 11.1 and 173.7 ± 67.0 μg/ml 2 h after intravenous administration of a single 500- or 2,000-mg dose, respectively. In 5 of the 10 patients given the 2,000-mg dose, peak moxalactam concentrations in the bile were 2 to 12 times higher than simultaneous serum levels, but considerable variation in the biliary excretion of maxalactam was observed among the individual patients.

Original language	English (US)
Pages (from-to)	231-234
Number of pages	4
Journal	Unknown Journal
Volume	20
Issue number	2
DOIs	https://doi.org/10.1128/AAC.20.2.231
State	Published - 1981

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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AU - Martinez, O. V.

AU - Levi, J. U.

AU - Livingstone, A.

AU - Malinin, T. I.

AU - Zeppa, R.

AU - Hutson, D.

AU - Einhorn, N.

PY - 1981

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Biliary excretion of moxalactam

Abstract

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